Histazyme, 60 Capsules
60 Capsules
May be a fit for
- Adults seeking enzyme support for histamine breakdown after meals
- Those who flush or feel uncomfortable after red wine or aged cheeses
- Individuals with low diamine oxidase activity looking to supplement DAO enzymes
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Histazyme by Amy Myers MD is a digestive enzyme blend formulated to support the breakdown of histamine from foods, featuring diamine oxidase (DAO) as its primary active compound. Designed for individuals who experience sensitivity to histamine-containing foods, it may help maintain comfortable digestion when consumed alongside meals.
Why It's Worth Considering: DAO enzyme supplementation directly targets histamine metabolism in the gut lumen, a targeted approach for those whose dietary histamine load outpaces their natural enzyme activity.
Amy Myers MD · 60 CapsulesMake it part of your routine.
Take 1 capsule no more than 15 minutes before consuming histamine-rich foods, or as recommended by your healthcare practitioner.
Important cautions & interactions
Product details
Supplement facts & complete label
Supplement Facts — Serving size: 2 capsules. Diamine oxidase (from porcine): 15 mg, providing more than 18,000 HDU. Other ingredients: microcrystalline cellulose, hypromellose vegetable capsule, L-leucine, silica.
Label directions
Take 1 capsule no more than 15 minutes before consuming histamine-rich foods, or as recommended by your healthcare practitioner.
Label cautions
Consult your healthcare practitioner before use, especially if pregnant or nursing. Keep out of reach of children. Avoid if allergic to pork or another ingredient. This product is not intended for immune-related food allergies, gluten sensitivity, or celiac disease.
Source: authorized supplier exact-SKU catalog label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking enzyme support for histamine breakdown after meals
- Those who flush or feel uncomfortable after red wine or aged cheeses
- Individuals with low diamine oxidase activity looking to supplement DAO enzymes
- People supporting histamine metabolism during high-histamine food seasons
Considerations
- Known allergy to any ingredient (check label)
- Currently pregnant or breastfeeding (consult healthcare provider)
- Taking prescription medications (check for interactions)
- Under 18 years of age (unless recommended by pediatrician)
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A few useful answers.
Research & further reading
More category questions
How should I store this supplement?
Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.
Can I take this with other supplements?
Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.
How long should I take this supplement?
Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.
When is the best time to take this?
Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.
How do I know if this supplement is working?
Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.