Douglas Labs

Pregnenolone (5mg), 100 Tablets

Douglas Labs Pregnenolone delivers 5 mg of pregnenolone per serving, a naturally occurring precursor hormone produced in the adrenal glands and brain.

4.4 across 1 sources

May be a fit for

  • Adults seeking pregnenolone support for cognitive clarity and mental sharpness
  • Individuals looking to maintain healthy pregnenolone levels associated with aging
  • Practitioners protocols requiring low-dose 5mg pregnenolone for sensitive patients
$18.99

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TabletsFormat
100 TabletsPack size
The essentials

A closer look.

Douglas Labs Pregnenolone delivers 5 mg of pregnenolone per serving, a naturally occurring precursor hormone produced in the adrenal glands and brain. This low-dose formulation supports neurological function, cognitive clarity, and healthy hormone balance for adults seeking gentle endocrine support.

Why It's Worth Considering: The 5 mg dose offers a conservative entry point suited for those new to pregnenolone or working with a practitioner to dial in hormonal support with precision. Douglas Labs is a practitioner-trusted brand with a long track record in clinical-grade manufacturing standards.

The Apotheca perspective

50+ signals. A clearer standard.

Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.

80OUT OF 100
Manufacturing6161
Lab verification6565
Transparency6060

Our score is an editorial assessment, not a product certification or a guarantee of results.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking pregnenolone support for cognitive clarity and mental sharpness
  • Individuals looking to maintain healthy pregnenolone levels associated with aging
  • Practitioners protocols requiring low-dose 5mg pregnenolone for sensitive patients
  • Those supporting hormone precursor balance with a conservative starting dose

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
From across the web

Real reviews. A wider perspective.

Customer reviews, social conversations and expert insights, with every source in view.

4.4/5Aggregate source rating
Marketplaces & brand websites
Amazon, iHerb and direct brand reviews
Social & community
Reddit, X, Instagram and TikTok
Video & creators
YouTube and creator perspectives

Coverage varies by product and brand.

105 product and brand ratings and mentions across 1 sources.

Explore the source sentiment summary

Reviews are practitioner recommendations listing Douglas Labs products with no direct user experience feedback on Pregnenolone 5mg specifically.

This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.

Good to know

A few useful answers.

Research & further reading

More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Douglas Labs - Pregnenolone (5mg), 100 Tablets Douglas Labs

Apotheca quality score

80/100

The overall score combines several sources of information. The individual dimensions below show where those signals are stronger or more limited; they are not a simple average of the overall score.

Manufacturing6161
Lab verification6565
Review consensus91.191.1
Practitioner signals71.071.0
Community signals5656
Transparency6060
See available brand signals
✓
Good manufacturing practices verifiedStandard
✓
Quality ingredients with verified sourcingGood
✓
Clean FDA regulatory recordNo issues
✓
Positive consumer reviews and community feedbackGood
✓
Authorized distribution channel verifiedDirect

Our score is an editorial assessment, not a product certification or a guarantee of results.

How our scoring works ↗