Magnesium Glycinate 400, 180 Capsules
Gaia Herbs Pro Magnesium Glycinate 400 delivers 400 mg of magnesium in its glycinate form, a chelated compound known for its favorable absorption profile and gentleness on the digestive tract.
May be a fit for
- Adults seeking magnesium glycinate for relaxed, restful sleep support
- Those with dietary magnesium gaps wanting a gentle, chelated form
- Individuals supporting muscle recovery with magnesium glycinate post-exercise
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Gaia Herbs Pro Magnesium Glycinate 400 delivers 400 mg of magnesium in its glycinate form, a chelated compound known for its favorable absorption profile and gentleness on the digestive tract. This formulation supports muscle relaxation, restful sleep, and healthy nervous system function, making it a practical option for adults with higher magnesium demands or those sensitive to other forms.
Why It's Worth Considering: Sourced from Gaia Herbs' practitioner-facing line, this product pairs the bioavailability advantages of glycinate chelation with the brand's commitment to clean, traceable ingredient sourcing.
Product details
Who it may suit
May be a fit for
- Adults seeking magnesium glycinate for relaxed, restful sleep support
- Those with dietary magnesium gaps wanting a gentle, chelated form
- Individuals supporting muscle recovery with magnesium glycinate post-exercise
- Practitioners protocols requiring 400mg magnesium glycinate with high GI tolerability
Considerations
- Severe kidney disease (impaired Mg excretion)
- Taking antibiotics — separate by 2+ hours
- Myasthenia gravis
- Already taking high-dose magnesium from another source
Compatibility & interactions
Works Well With
Take Separately From
What to expect over time
Sleep Improvement
Faster sleep onset, deeper REM
Cramp Relief
Reduced nighttime cramps and muscle tension
Mood & Calm
Lower baseline anxiety, improved stress resilience
Serum Optimization
Measurable RBC magnesium improvement
Based on clinical research on magnesium supplementation. Effects are cumulative with consistent daily use.
Compare the options
Compare Magnesium Forms
Which form is right for you?
| Feature | Glycinate | Citrate | Oxide | L-Threonate | Taurate |
|---|---|---|---|---|---|
| Bioavailability | High (chelated) | Moderate-High | Low (4-5%) | Moderate | Moderate-High |
| Best For | Sleep, anxiety, cramps | Constipation, general | Budget (low absorption) | Cognitive function | Heart health |
| GI Tolerance | Excellent | Moderate | Poor (laxative) | Good | Good |
| Laxative Effect | None | Mild–Moderate | Strong | None | None |
| Evidence | Strong | Strong | Weak | Emerging | Moderate |
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A few useful answers.
Research & further reading
More category questions
What is the best form of magnesium to take?
Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.
Does magnesium glycinate cause diarrhea?
No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.
When is the best time to take magnesium?
Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works — glycinate does not require food for absorption.
How do I know if I am magnesium deficient?
Standard blood tests (serum magnesium) are unreliable — only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.
Can I take magnesium with other supplements?
Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.
How much magnesium should I take daily?
The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.