Capsules · 90 capsules · 45 servings · $0.82/serving
Serving Size:
2 Capsules
Amount Per Serving:
Total Carbohydrate ... <1 g
Barberry (Berberis vulgaris) (root) Extract ... 400 mg
Oregon Grape (Berberis aquifolium) (root and stem) Extract ... 400 mg
Goldenseal (Hydrastis canadensis) (root and rhizome) Extract standardized to contain 5% total alkaloids including berberine and hydrastine ... 100 mg
Other ingredients: plant-derived capsule (hypromellose), cellulose, magnesium stearate, silica.
Take 2 capsules three times daily, or as recommended by your healthcare professional.
Do not use if pregnant or nursing. If you have diabetes or are taking prescription drugs, consult a healthcare professional before use. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
Source: Fullscript original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Berberine Complex by Integrative Therapeutics combines berberine with complementary botanicals to support healthy blood sugar metabolism, lipid levels already within normal range, and gastrointestinal balance. Formulated for adults seeking multi-pathway metabolic support, this product reflects Integrative Therapeutics' practitioner-grade development standards.
Why It's Worth Considering: The complex formulation pairs berberine with synergistic ingredients designed to enhance its metabolic activity, a thoughtful approach for those who want more than a standalone alkaloid extract.
Take 2 capsules three times daily, or as recommended by your healthcare professional.
Head-to-head clinical trials show berberine 500mg 3x/day produces comparable HbA1c reduction (0.5-0.9%) and fasting glucose reduction to metformin 500mg 3x/day. Berberine also reduces LDL cholesterol and triglycerides, an effect metformin doesn't have. However, berberine is a supplement, not a drug, and should not replace prescribed medication without physician guidance.
Take 500mg 2-3 times daily with meals. The key is splitting the dose, berberine has a short half-life (~5 hours) and taking it with each meal maximizes the post-meal blood sugar benefit. Start with 500mg once daily and increase over 2 weeks to reduce GI side effects (which are similar to metformin).
Common: GI discomfort, diarrhea, constipation, gas (similar to metformin, usually resolves in 1-2 weeks). Berberine can lower blood sugar significantly, monitor if diabetic. It also inhibits CYP3A4 liver enzyme, which affects metabolism of many drugs (statins, blood thinners, antidepressants). Check drug interactions carefully.
Most studies are 3-6 months. Some practitioners recommend cycling: 8 weeks on, 4 weeks off, to maintain effectiveness and allow the gut microbiome to rebalance (berberine has antimicrobial properties). Long-term continuous use appears safe in studies up to 2 years, but cycling is a reasonable precaution.
Apotheca is analyzing ingredient interactions, stacking compatibility, and timing recommendations for Integrative Therapeutics - Berberine Complex. This data will be available soon.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
