Magnesium Glycinate Plus, 120 Tablets
Magnesium Glycinate Plus from Integrative Therapeutics delivers magnesium in its glycinate chelate form, a highly absorbable, gentle-on-the-stomach format that supports muscle relaxation, nervous system balance, and restful sleep.
May be a fit for
- Adults seeking magnesium glycinate in a highly absorbable chelated form
- Individuals supporting healthy muscle relaxation and recovery with magnesium glycinate
- Practitioner protocols requiring magnesium glycinate for patients with gastrointestinal sensitivity
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Magnesium Glycinate Plus from Integrative Therapeutics delivers magnesium in its glycinate chelate form, a highly absorbable, gentle-on-the-stomach format that supports muscle relaxation, nervous system balance, and restful sleep. Formulated by a practitioner-grade brand, it's well-suited for adults seeking reliable magnesium repletion without the laxative effect common to other forms.
Why It's Worth Considering: The glycinate chelate form binds magnesium to the amino acid glycine, which may enhance intestinal absorption and tolerability compared to oxide or citrate forms, a meaningful distinction for those with sensitive digestion or higher repletion needs.
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Product details
Who it may suit
May be a fit for
- Adults seeking magnesium glycinate in a highly absorbable chelated form
- Individuals supporting healthy muscle relaxation and recovery with magnesium glycinate
- Practitioner protocols requiring magnesium glycinate for patients with gastrointestinal sensitivity
- Those using magnesium glycinate to help maintain healthy sleep quality and calm
Considerations
- Severe kidney disease (impaired Mg excretion)
- Taking antibiotics — separate by 2+ hours
- Myasthenia gravis
- Already taking high-dose magnesium from another source
Compatibility & interactions
Works Well With
Take Separately From
What to expect over time
Sleep Improvement
Faster sleep onset, deeper REM
Cramp Relief
Reduced nighttime cramps and muscle tension
Mood & Calm
Lower baseline anxiety, improved stress resilience
Serum Optimization
Measurable RBC magnesium improvement
Based on clinical research on magnesium supplementation. Effects are cumulative with consistent daily use.
Compare the options
Compare Magnesium Forms
Which form is right for you?
| Feature | Glycinate | Citrate | Oxide | L-Threonate | Taurate |
|---|---|---|---|---|---|
| Bioavailability | High (chelated) | Moderate-High | Low (4-5%) | Moderate | Moderate-High |
| Best For | Sleep, anxiety, cramps | Constipation, general | Budget (low absorption) | Cognitive function | Heart health |
| GI Tolerance | Excellent | Moderate | Poor (laxative) | Good | Good |
| Laxative Effect | None | Mild–Moderate | Strong | None | None |
| Evidence | Strong | Strong | Weak | Emerging | Moderate |
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679 product and brand ratings and mentions across 8 sources.
These are broader practitioner and research perspectives. They may discuss the brand or other products, rather than this exact formula.
Explore the source sentiment summary
Overwhelmingly positive consensus praising magnesium glycinate as life-changing, especially for sleep and stress, with high bioavailability noted as a key advantage.
This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.
A few useful answers.
Research & further reading
More category questions
What is the best form of magnesium to take?
Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.
Does magnesium glycinate cause diarrhea?
No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.
When is the best time to take magnesium?
Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works — glycinate does not require food for absorption.
How do I know if I am magnesium deficient?
Standard blood tests (serum magnesium) are unreliable — only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.
Can I take magnesium with other supplements?
Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.
How much magnesium should I take daily?
The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.