Integrative Therapeutics

Panplex-2 Phase, 180 Capsules

Panplex-2 Phase by Integrative Therapeutics is a dual-action digestive enzyme formula combining pancreatic enzymes with ox bile and betaine HCl to support both upper and lower digestive function.

4.6 across 2 sources

May be a fit for

  • Adults seeking bile salt and pancreatic enzyme support for fat digestion
  • Individuals with sluggish upper GI function needing dual-phase digestive enzyme coverage
  • Practitioners protocols requiring combined hydrochloric acid and pancreatin enzyme formulas
$49.99

30-day money-back guarantee
Save together with Wellness Circles

Invite friends or family to a Wellness Circle. Your group can unlock savings together. See current tiers and terms before joining.

Explore Wellness Circles
CapsulesFormat
180 CapsulesPack size
The essentials

A closer look.

Panplex-2 Phase by Integrative Therapeutics is a dual-action digestive enzyme formula combining pancreatic enzymes with ox bile and betaine HCl to support both upper and lower digestive function. Designed for individuals who may have difficulty breaking down fats, proteins, and carbohydrates, it addresses two phases of digestion in a single product.

Why It's Worth Considering: The inclusion of both pancreatin and bile salts in one formula is less common and may better support those with compromised fat digestion or low stomach acid output, a distinction that makes it relevant in clinical nutrition contexts.

The Apotheca perspective

50+ signals. A clearer standard.

Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.

83OUT OF 100
Manufacturing7878
Lab verification6565
Transparency6363

Our score is an editorial assessment, not a product certification or a guarantee of results.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking bile salt and pancreatic enzyme support for fat digestion
  • Individuals with sluggish upper GI function needing dual-phase digestive enzyme coverage
  • Practitioners protocols requiring combined hydrochloric acid and pancreatin enzyme formulas
  • Those supporting nutrient absorption from high-protein or high-fat meals

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
From across the web

Real reviews. A wider perspective.

Customer reviews, social conversations and expert insights, with every source in view.

4.6/5Aggregate source rating
Marketplaces & brand websites
Amazon, iHerb and direct brand reviews
Social & community
Reddit, X, Instagram and TikTok
Video & creators
YouTube and creator perspectives

Coverage varies by product and brand.

455 product and brand ratings and mentions across 2 sources.

Explore the source sentiment summary

Integrative Therapeutics is widely trusted by both practitioners and users, with consistent positive outcomes across digestive, hormonal, and wellness products.

This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.

Good to know

A few useful answers.

Research & further reading

More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Integrative Therapeutics - Panplex-2 Phase, 180 Capsules Integrative Therapeutics

Apotheca quality score

83/100

The overall score combines several sources of information. The individual dimensions below show where those signals are stronger or more limited; they are not a simple average of the overall score.

Manufacturing7878
Lab verification6565
Review consensus98.098.0
Practitioner signals58.058.0
Community signals6868
Transparency6363
See available brand signals
✓
Good manufacturing practices verifiedStandard
✓
Quality ingredients with verified sourcingGood
✓
Clean FDA regulatory recordNo issues
✓
Positive consumer reviews and community feedbackGood
✓
Authorized distribution channel verifiedDirect

Our score is an editorial assessment, not a product certification or a guarantee of results.

How our scoring works ↗