Integrative Therapeutics

Petadolex (Patented Brain Support), 60 Softgels

Petadolex by Integrative Therapeutics delivers a standardized extract of Petasites hybridus (butterbur root) in a patented CO₂-extraction process that removes pyrrolizidine alkaloids (PAs), compounds naturally present in raw butterbur that are unsuitable for regular consumption.

May be a fit for

  • Adults seeking butterbur extract support for occasional head tension
  • Individuals with frequent neurological stress looking for petasites hybridus support
  • Practitioners protocols requiring PA-free standardized butterbur for sensitive patients
$61.99

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SoftgelsFormat
60 SoftgelsPack size
The essentials

A closer look.

Petadolex by Integrative Therapeutics delivers a standardized extract of Petasites hybridus (butterbur root) in a patented CO₂-extraction process that removes pyrrolizidine alkaloids (PAs), compounds naturally present in raw butterbur that are unsuitable for regular consumption. Each softgel provides 75 mg of the clinically researched Petadolex® extract, standardized to petasin and isopetasin, and is formulated to support healthy neurological comfort and brain function. It is designed for adults seeking evidence-informed botanical support.

Why It's Worth Considering: The PA-free certification and decades of clinical research behind the Petadolex® extract set this formulation apart from generic butterbur products; Integrative Therapeutics applies practitioner-grade quality standards throughout manufacturing.

Integrative Therapeutics - Petadolex (Patented Brain Support), 60 SoftgelsIntegrative Therapeutics · 60 Softgels
Make it part of your day

Make it part of your routine.

Adults swallow 1 softgel three times daily. Do not bite or chew.

Important cautions & interactions
Do not use if you are pregnant, nursing, or have a liver disorder. If you are taking any medications, consult a healthcare professional before use. Discontinue use and consult a healthcare professional if you develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
Read the complete label
Inside the formula

Product details

Supplement facts & complete label

Supplement Facts
Serving Size: 1 softgel — Amount / Serving — %DV
Purple Butterbur (Petasites hybridus) (Petadolex® brand) (root) Extract standardized to contain 7.5 mg petasins including petasin and isopetasin — 50mg — **
** Daily Value (DV) not established.
† Percent Daily Values are based on a 2,000 calorie diet.
Other ingredients: medium chain triglycerides, gelatin, glycerin, sorbitol, purified water, riboflavin color

Label directions

Adults swallow 1 softgel three times daily. Do not bite or chew.

Label cautions

Do not use if you are pregnant, nursing, or have a liver disorder. If you are taking any medications, consult a healthcare professional before use. Discontinue use and consult a healthcare professional if you develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Source: Integrative Therapeutics manufacturer label and directions · September 06, 2026. Formulas and labels can change. Check the packaging you receive.

Who it may suit

May be a fit for

  • Adults seeking butterbur extract support for occasional head tension
  • Individuals with frequent neurological stress looking for petasites hybridus support
  • Practitioners protocols requiring PA-free standardized butterbur for sensitive patients
  • Those supporting healthy cerebrovascular function with clinically studied Petadolex extract

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
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How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Integrative Therapeutics - Petadolex (Patented Brain Support), 60 Softgels