Integrative Therapeutics

Petadolex (Patented Brain Support)

Softgels · 60 softgels · 60 servings · $1.03/serving

  • Adults seeking butterbur extract support for occasional head tension
  • Individuals with frequent neurological stress looking for petasites hybridus support
  • Practitioners protocols requiring PA-free standardized butterbur for sensitive patients
  • Brand Trust · 92% of verified reviews
★★★★☆ 4.4 (27) 2 sources
See breakdown →
Manufacturing78
Lab Verification65
Review Consensus89.2
Brand-verified ·Good manufacturing practices verifiedQuality ingredients with verified sourcingClean FDA regulatory recordPositive consumer reviews and community feedbackAuthorized distribution channel verified
$61.99
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Ingredients & product label

Supplement Facts
Serving Size: 1 softgel — Amount / Serving — %DV
Purple Butterbur (Petasites hybridus) (Petadolex® brand) (root) Extract standardized to contain 7.5 mg petasins including petasin and isopetasin — 50mg — **
** Daily Value (DV) not established.
† Percent Daily Values are based on a 2,000 calorie diet.
Other ingredients: medium chain triglycerides, gelatin, glycerin, sorbitol, purified water, riboflavin color

Label directions

Adults swallow 1 softgel three times daily. Do not bite or chew.

Label cautions

Do not use if you are pregnant, nursing, or have a liver disorder. If you are taking any medications, consult a healthcare professional before use. Discontinue use and consult a healthcare professional if you develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Ingredient information is provided above. A clear label image is not available yet.

View original supplier image (quality may be limited)

Source: Integrative Therapeutics manufacturer label and directions · September 06, 2026. Formulas and labels can change. Check the packaging you receive.

About Integrative Therapeutics - Petadolex (Patented Brain Support)

Petadolex by Integrative Therapeutics delivers a standardized extract of Petasites hybridus (butterbur root) in a patented CO₂-extraction process that removes pyrrolizidine alkaloids (PAs), compounds naturally present in raw butterbur that are unsuitable for regular consumption. Each softgel provides 75 mg of the clinically researched Petadolex® extract, standardized to petasin and isopetasin, and is formulated to support healthy neurological comfort and brain function. It is designed for adults seeking evidence-informed botanical support.

Why It's Worth Considering: The PA-free certification and decades of clinical research behind the Petadolex® extract set this formulation apart from generic butterbur products; Integrative Therapeutics applies practitioner-grade quality standards throughout manufacturing.

Why Gabriel Recommends This

Quality & Trust Score: 81 Moderate Evidence
Quality Verified
Integrative Therapeutics products are evaluated across 50+ quality signals including manufacturing standards, lab verification, and ingredient sourcing transparency.
Label details
Ingredient amounts and serving sizes are shown in the product label section when supplier information is available.
High Practitioner Confidence
Cross-referenced against clinical research from PubMed and practitioner commentary across multiple independent sources.
Manufacturing Standards
Integrative Therapeutics maintains GMP-certified manufacturing. Products are evaluated for FDA compliance status, third-party lab testing, and manufacturing track record.
Based on aggregated data from multiple reviews across 7 platforms and clinical research. How the Quality & Trust Score works →
Recommendation generated by Gabriel AI based on publicly available practitioner commentary and quality data. Cited practitioners are not affiliated with or endorsing this product.

How to Take

Adults swallow 1 softgel three times daily. Do not bite or chew.

Who Benefits

Best For

  • Adults seeking butterbur extract support for occasional head tension
  • Individuals with frequent neurological stress looking for petasites hybridus support
  • Practitioners protocols requiring PA-free standardized butterbur for sensitive patients
  • Those supporting healthy cerebrovascular function with clinically studied Petadolex extract

Cautions

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)

Frequently Asked Questions

  • Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements, some probiotics and oils require refrigeration.

  • Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

  • Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

  • Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

  • Track your specific health goals, energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Real Reviews. Real Sources.

4.4
27 reviews
5 star
55%
4 star
25%
3 star
10%
2 star
6%
1 star
4%
All (27)
0 Clinical Research
iHerb
0 iHerb
Amazon
26 Amazon
0 Practitioners
Reddit
1 Reddit
X
0 X
TikTok
0 TikTok
Instagram
0 Instagram
Substack
0 Substack
27 ratings aggregated across 2 sources · full-text reviews below
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Apotheca's Analysis · 50+ Signals Across 6 Dimensions
Integrative Therapeutics is highly regarded by both consumers and practitioners, with consistent positive mentions across multiple products and use cases.
Brand Trust
92%
Efficacy
85%
Practitioner Approval
90%
Value
70%
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Compatibility Guide

Compatibility Data Loading

Apotheca is analyzing ingredient interactions, stacking compatibility, and timing recommendations for Integrative Therapeutics - Petadolex (Patented Brain Support). This data will be available soon.

Research Behind This

Integrative Therapeutics Product Quality Assessment
Quality & Trust Score Analysis
This product has been evaluated across 50+ quality signals including third-party testing, manufacturing standards, ingredient sourcing, and clinical evidence. Integrative Therapeutics products are analyzed against our comprehensive database of practitioner-grade supplements.
Practitioner Network Endorsement Data
Apotheca Practitioner Intelligence
Integrative Therapeutics is referenced across our practitioner network of clinical recommendations, YouTube health channels, and professional forums. Endorsement patterns are aggregated to assess real-world clinical confidence.

Practitioner Insights

Who This Is For

✓ Great For

Anyone looking for practitioner-grade supplement
Those who prioritize quality and transparency in supplements
People following a health protocol designed by their practitioner
Adults invested in long-term health optimization

⚠ Important Notes

Always consult your healthcare provider before starting any supplement
Check for interactions with current medications
If pregnant or nursing, seek professional guidance first
Compare options using Apotheca's AI to find the best fit for your goals
Integrative Therapeutics is part of Gabriel's curated marketplace of practitioner-grade supplement brands. Every product from Integrative Therapeutics is evaluated across 50+ quality signals including manufacturing standards, ingredient sourcing, third-party testing, and clinical evidence.
Gabriel VerifiedQuality Analyzed

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Integrative Therapeutics
Integrative Therapeutics - Petadolex (Patented Brain Support)
Quality & Trust Score
Strong quality signals. Meets recommended thresholds across most pillars.
Last updated: September 08, 2026
Score Breakdown
Manufacturing & GMP
78
Lab Verification
65
Review Consensus
89.2
Practitioner Confidence
58.0
Community & Social
68
Transparency
63
Consumer & Practitioner Intelligence
★★★★☆ 4.4 from 27 reviews across 2 sources
Amazon 26Community 1+
Aggregated from verified purchases, practitioner clinical notes, and real-world outcome data
Scored across 50+ quality dimensions from 15+ independent databases. No brand can pay to influence their score. No sponsored rankings. Ever.
See how this product scores against your health profile · How the Quality & Trust Score works