Capsules · 100 capsules · 100 servings · $0.35/serving
Serving Size:
1 Capsule
Amount Per Serving:
Vitamin B6 ... 30mg
(as pyridoxal 5-phosphate)
Magnesium ... 100mg
(as Albion® magnesium bisglycinate chelate, magnesium oxide*)
Other Ingredients:
Vegetarian capsule (hydroxypropyl methylcellulose, water) and ascorbyl palmitate.
Made without common allergens | Non-GMO | Vegan
No synthetic colors or flavors
Caution:
Do not use if shrinkwrap is broken or missing. Store in a cool, dry place away from direct light.
Keep out of reach of children.
Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.
Ingredient information is provided above. A clear label image is not available yet.
View original supplier image (quality may be limited)Source: Fullscript supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
P-5-P Plus with Magnesium from Klaire Labs/SFI Health provides pyridoxal-5-phosphate, the active, coenzyme form of vitamin B6, paired with magnesium to support neurotransmitter synthesis, amino acid metabolism, and nervous system function. Unlike standard pyridoxine, P-5-P requires no hepatic conversion, making it a practical choice for individuals with impaired B6 metabolism or those seeking a more directly usable form.
Why It's Worth Considering: Klaire Labs formulates to practitioner-grade standards, and pairing P-5-P with magnesium reflects the synergistic role both nutrients play in enzymatic pathways supporting mood and metabolic balance.
Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.
| Feature | Glycinate | Citrate | Oxide | L-Threonate | Taurate |
|---|---|---|---|---|---|
| Bioavailability | High (chelated) | Moderate-High | Low (4-5%) | Moderate | Moderate-High |
| Best For | Sleep, anxiety, cramps | Constipation, general | Budget (low absorption) | Cognitive function | Heart health |
| GI Tolerance | Excellent | Moderate | Poor (laxative) | Good | Good |
| Laxative Effect | None | Mild–Moderate | Strong | None | None |
| Evidence | Strong | Strong | Weak | Emerging | Moderate |
Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.
No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.
Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works, glycinate does not require food for absorption.
Standard blood tests (serum magnesium) are unreliable, only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.
Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.
The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
