Klaire Labs/SFI Health

SAMe 200

Tablets · 60 tablets · 60 servings · $0.99/serving

  • Adults seeking SAMe support for occasional low mood and emotional balance
  • Individuals looking to maintain healthy joint comfort with SAMe supplementation
  • Those supporting liver methylation pathways with clinically dosed SAMe 200mg
Quality & Trust Score
87 Strong Evidence
★★★★☆ 4.3 (1.2K) 1 sources
See breakdown →
Manufacturing96
Lab Verification83
Review Consensus91.7
Brand-verified ·Third-party lab tested (heavy metals, contaminants)GMP-certified manufacturing by Klaire Labs/SFI HealthPremium ingredient sourcing with bioavailable formsClean FDA regulatory recordAuthorized distribution channel verified
$59.99
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Ingredients & product label

Serving Size:
1 Tablet

Amount Per Serving:

S-Adenosyl L-Methionine (from 400 mg of S-Adenosyl L-Methionine tosylate disulfate) ... 200 mg*

Other Ingredients:
Microcrystalline cellulose, magnesium silicate, food glaze, magnesium stearate, stearic acid, magnesium hydroxide, glycerol, silicon dioxide, arginine, sodium alginate, and calcium oxide.

Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, soybeans, and sesame. No synthetic colors, flavors, or preservatives. Non-GMO.

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your healthcare professional before using this product.  Individuals being treated for neurological conditions, including those using prescribed medications such as antidepressants, serotonin reuptake inhibitors, and monoamine oxidase (MAO) inhibitors should consult their healthcare professional before using this product. Individuals with bipolar disorder or manic depression should not take SAMe 200 unless under medical supervision. Keep out of reach of children.

Label directions

Adults take 1 tablet, 1 to 6 times daily on an empty stomach or as directed by a healthcare professional.

Ingredient information is provided above. A clear label image is not available yet.

View original supplier image (quality may be limited)

Source: Fullscript supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.

About Klaire Labs/SFI Health - SAMe 200

SAMe 200 by Klaire Labs/SFI Health delivers S-adenosyl-L-methionine (SAMe) at a 200 mg dose per tablet, a naturally occurring compound involved in methylation pathways that supports mood balance, joint comfort, and healthy liver function. It's particularly well-suited for adults seeking targeted methyl-donor support as part of a broader wellness protocol.

Why It's Worth Considering: Klaire Labs uses a stabilized, enteric-coated tablet form to protect SAMe from degradation in the stomach, supporting absorption in the small intestine, an important consideration given SAMe's inherent instability.

Why Gabriel Recommends This

Quality & Trust Score: 87 Strong Evidence
Quality Verified
Klaire Labs/SFI Health products are evaluated across 50+ quality signals including manufacturing standards, lab verification, and ingredient sourcing transparency.
Label details
Ingredient amounts and serving sizes are shown in the product label section when supplier information is available.
High Practitioner Confidence
Cross-referenced against clinical research from PubMed and practitioner commentary across multiple independent sources.
Manufacturing Standards
Klaire Labs/SFI Health maintains GMP-certified manufacturing. Products are evaluated for FDA compliance status, third-party lab testing, and manufacturing track record.
Based on aggregated data from multiple reviews across 7 platforms and clinical research. How the Quality & Trust Score works →
Recommendation generated by Gabriel AI based on publicly available practitioner commentary and quality data. Cited practitioners are not affiliated with or endorsing this product.

How to Take

Adults take 1 tablet, 1 to 6 times daily on an empty stomach or as directed by a healthcare professional.

Who Benefits

Best For

  • Adults seeking SAMe support for occasional low mood and emotional balance
  • Individuals looking to maintain healthy joint comfort with SAMe supplementation
  • Those supporting liver methylation pathways with clinically dosed SAMe 200mg
  • Practitioner protocols requiring pharmaceutical-grade SAMe for cognitive and mood applications

Cautions

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)

Frequently Asked Questions

  • Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements, some probiotics and oils require refrigeration.

  • Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

  • Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

  • Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

  • Track your specific health goals, energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Real Reviews. Real Sources.

4.3
1165 reviews
5 star
55%
4 star
25%
3 star
10%
2 star
6%
1 star
4%
All (1165)
0 Clinical Research
iHerb
0 iHerb
Amazon
1165 Amazon
0 Practitioners
Reddit
0 Reddit
X
0 X
TikTok
0 TikTok
Instagram
0 Instagram
Substack
0 Substack
1.2K ratings aggregated across 1 sources · full-text reviews below
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Apotheca's Analysis · 50+ Signals Across 6 Dimensions
SAMe 200 was scored across 50+ quality signals spanning manufacturing standards, lab verification, review consensus, practitioner confidence, community sentiment, and transparency. The Quality & Trust Score of 87 reflects data aggregated from 1 independent sources and 1165 total reviews. No brand can pay to influence this score.
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Compatibility Guide

Compatibility Data Loading

Apotheca is analyzing ingredient interactions, stacking compatibility, and timing recommendations for Klaire Labs/SFI Health - SAMe 200. This data will be available soon.

Research Behind This

Klaire Labs/SFI Health Product Quality Assessment
Quality & Trust Score Analysis
This product has been evaluated across 50+ quality signals including third-party testing, manufacturing standards, ingredient sourcing, and clinical evidence. Klaire Labs/SFI Health products are analyzed against our comprehensive database of practitioner-grade supplements.
Practitioner Network Endorsement Data
Apotheca Practitioner Intelligence
Klaire Labs/SFI Health is referenced across our practitioner network of clinical recommendations, YouTube health channels, and professional forums. Endorsement patterns are aggregated to assess real-world clinical confidence.

Practitioner Insights

Who This Is For

✓ Great For

Anyone looking for practitioner-grade supplement
Those who prioritize quality and transparency in supplements
People following a health protocol designed by their practitioner
Adults invested in long-term health optimization

⚠ Important Notes

Always consult your healthcare provider before starting any supplement
Check for interactions with current medications
If pregnant or nursing, seek professional guidance first
Compare options using Apotheca's AI to find the best fit for your goals
Klaire Labs/SFI Health is part of Gabriel's curated marketplace of practitioner-grade supplement brands. Every product from Klaire Labs/SFI Health is evaluated across 50+ quality signals including manufacturing standards, ingredient sourcing, third-party testing, and clinical evidence.
Gabriel VerifiedQuality Analyzed

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Klaire Labs/SFI Health
Klaire Labs/SFI Health - SAMe 200
87
Strong Evidence
Quality & Trust Score
Strong quality signals. Meets recommended thresholds across most pillars.
Last updated: September 08, 2026
Score Breakdown
Manufacturing & GMP
96
Lab Verification
83
Review Consensus
91.7
Practitioner Confidence
50
Community & Social
57
Transparency
60
Consumer & Practitioner Intelligence
★★★★☆ 4.3 from 1165 reviews across 1 sources
Amazon 1165
Aggregated from verified purchases, practitioner clinical notes, and real-world outcome data
Scored across 50+ quality dimensions from 15+ independent databases. No brand can pay to influence their score. No sponsored rankings. Ever.
See how this product scores against your health profile · How the Quality & Trust Score works