Life Extension

Citicoline (CDP-Choline), 60 Capsules

Life Extension's Citicoline delivers CDP-Choline (cytidine 5'-diphosphocholine), a bioavailable form of choline that supports cognitive function, memory, and attention.

4.5 across 4 sources

May be a fit for

  • Adults seeking citicoline support for everyday mental focus and clarity
  • Those looking to maintain choline levels for neurological function
  • Individuals supporting cognitive performance during demanding work or study
$34.99

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CapsulesFormat
60 CapsulesPack size
The essentials

A closer look.

Life Extension's Citicoline delivers CDP-Choline (cytidine 5'-diphosphocholine), a bioavailable form of choline that supports cognitive function, memory, and attention. Unlike standard choline supplements, CDP-Choline provides two neuroactive components, choline and cytidine, which may help maintain healthy phosphatidylcholine levels in brain cell membranes. It's well-suited for adults seeking neurological support and mental clarity.

Why It's Worth Considering: Life Extension uses Cognizin®, a patented, clinically studied form of citicoline recognized for consistent purity and bioavailability in research settings.

The Apotheca perspective

50+ signals. A clearer standard.

Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.

84OUT OF 100
Manufacturing4343
Lab verification7878
Transparency6565

Our score is an editorial assessment, not a product certification or a guarantee of results.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking citicoline support for everyday mental focus and clarity
  • Those looking to maintain choline levels for neurological function
  • Individuals supporting cognitive performance during demanding work or study
  • Older adults interested in CDP-choline for healthy brain aging support

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
From across the web

Real reviews. A wider perspective.

Customer reviews, social conversations and expert insights, with every source in view.

4.5/5Aggregate source rating
Marketplaces & brand websites
Amazon, iHerb and direct brand reviews
Social & community
Reddit, X, Instagram and TikTok
Video & creators
YouTube and creator perspectives

Coverage varies by product and brand.

2542 product and brand ratings and mentions across 4 sources.

Explore the source sentiment summary

Practitioners broadly endorse choline for cognitive support and development; Life Extension seen as reputable, though few reviews target CDP-Choline specifically.

This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.

Good to know

A few useful answers.

Research & further reading

More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Life Extension - Citicoline (CDP-Choline), 60 Capsules Life Extension

Apotheca quality score

84/100

The overall score combines several sources of information. The individual dimensions below show where those signals are stronger or more limited; they are not a simple average of the overall score.

Manufacturing4343
Lab verification7878
Review consensus97.597.5
Practitioner signals61.061.0
Community signals6868
Transparency6565
See available brand signals
✓
Quality ingredients with verified sourcingGood
✓
Clean FDA regulatory recordNo issues
✓
Positive consumer reviews and community feedbackGood
✓
Authorized distribution channel verifiedDirect

Our score is an editorial assessment, not a product certification or a guarantee of results.

How our scoring works ↗