Metagenics

AdvaClear®, 42 Capsules

AdvaClear® by Metagenics is a practitioner-formulated supplement designed to support balanced Phase I and Phase II liver detoxification pathways.

May be a fit for

  • Adults supporting Phase I and Phase II liver detoxification pathways
  • Practitioners protocols requiring balanced biotransformation nutrient cofactors
  • Individuals seeking sulforaphane and B-vitamin support for hepatic metabolism
$42.99

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CapsulesFormat
42 CapsulesPack size
The essentials

A closer look.

AdvaClear® by Metagenics is a practitioner-formulated supplement designed to support balanced Phase I and Phase II liver detoxification pathways. It combines targeted B vitamins, antioxidants, and botanicals, including milk thistle, green tea extract, and cruciferous vegetable compounds, to help maintain healthy hepatic biotransformation activity. Suited for individuals undergoing structured detoxification protocols under clinical guidance.

Why It's Worth Considering: Metagenics formulated AdvaClear® specifically to modulate both detox phases concurrently, a distinction from single-pathway liver products, making it a common choice in functional medicine settings.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults supporting Phase I and Phase II liver detoxification pathways
  • Practitioners protocols requiring balanced biotransformation nutrient cofactors
  • Individuals seeking sulforaphane and B-vitamin support for hepatic metabolism
  • Those undergoing structured detox programs needing antioxidant enzyme support

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
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Good to know

A few useful answers.

Research & further reading

More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Metagenics - AdvaClear®, 42 Capsules