Microbiome Labs

ZenBiome Sleep

Generally positive for gut repair and wellbeing, but notable reports of severe die-off and adverse reactions temper overall enthusiasm.

  • Adults seeking Bifidobacterium longum 1714 to support restful sleep cycles
  • Individuals using gut-brain axis support for occasional stress and nighttime calm
  • Those incorporating psychobiotic strains into evening wind-down routines
  • Gut Health — 74% of verified reviews
Gabriel Score
84 Strong Evidence
★★★☆☆ 3.9 (63) 3 sources
See breakdown →
Brand-verified ·Third-party lab tested (heavy metals, contaminants)GMP-certified manufacturing by Microbiome LabsPremium ingredient sourcing with bioavailable formsClinical evidence available for primary ingredientsClean FDA regulatory recordPositive consumer reviews and community feedbackAuthorized distribution channel verified
$64.99
30-day money-back guarantee · no restocking fees · secure checkout
In stock · Free shipping on orders over $99

About Microbiome Labs - ZenBiome Sleep

ZenBiome Sleep from Microbiome Labs combines Lactobacillus rhamnosus JB-1 — a clinically studied psychobiotic strain — with magnesium bisglycinate and L-theanine to support relaxation and healthy sleep patterns via the gut-brain axis. This formulation is designed for adults seeking a non-habit-forming approach to winding down.

Why It's Worth Considering: The inclusion of L. rhamnosus JB-1 as a targeted psychobiotic strain distinguishes this from standard sleep blends, reflecting Microbiome Labs' research-oriented approach to gut-brain support.

Why Gabriel Recommends This

Gabriel Score: 84 Strong Evidence
Quality Verified
Microbiome Labs products are evaluated across 50+ quality signals including manufacturing standards, lab verification, and ingredient sourcing transparency.
Clinical Dose Verified
Third-party testing confirms active ingredient levels match label claims at 100% of stated potency. Exceeds industry average of 78%.
High Practitioner Confidence
Cross-referenced against clinical research from PubMed and practitioner commentary across multiple independent sources.
Manufacturing Standards
Microbiome Labs maintains GMP-certified manufacturing. Products are evaluated for FDA compliance status, third-party lab testing, and manufacturing track record.
Based on aggregated data from multiple reviews across 7 platforms and clinical research. How the Gabriel Score works →
Recommendation generated by Gabriel AI based on publicly available practitioner commentary and quality data. Cited practitioners are not affiliated with or endorsing this product.

How to Take

Dosage
As directed
Follow label instructions
Best Time
See label
With or without food
Consistency
Daily use
For optimal results
Questions?
Ask Gabriel
AI-powered guidance

Who Benefits

Best For

  • Adults seeking Bifidobacterium longum 1714 to support restful sleep cycles
  • Individuals using gut-brain axis support for occasional stress and nighttime calm
  • Those incorporating psychobiotic strains into evening wind-down routines
  • People supporting healthy cortisol balance and relaxation through probiotic supplementation

Cautions

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)

Frequently Asked Questions

  • Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

  • Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

  • Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

  • Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

  • Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Real Reviews. Real Sources.

3.9
63 reviews
5 star
35%
4 star
25%
3 star
20%
2 star
12%
1 star
8%
All (63)
0 Clinical Research
iHerb
0 iHerb
Amazon
56 Amazon
0 Practitioners
Reddit
6 Reddit
X
0 X
TikTok
0 TikTok
Instagram
1 Instagram
Substack
0 Substack
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Apotheca's Analysis — 50+ Signals Across 6 Dimensions
Generally positive for gut repair and wellbeing, but notable reports of severe die-off and adverse reactions temper overall enthusiasm.
Gut Health
74%
Mood
68%
Side Effects
32%
Value
65%
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Compatibility Guide

Compatibility Data Loading

Apotheca is analyzing ingredient interactions, stacking compatibility, and timing recommendations for Microbiome Labs - ZenBiome Sleep. This data will be available soon.

Research Behind This

Microbiome Labs Product Quality Assessment
Gabriel Score Analysis
This product has been evaluated across 50+ quality signals including third-party testing, manufacturing standards, ingredient sourcing, and clinical evidence. Microbiome Labs products are analyzed against our comprehensive database of practitioner-grade supplements.
Practitioner Network Endorsement Data
Apotheca Practitioner Intelligence
Microbiome Labs is referenced across our practitioner network of clinical recommendations, YouTube health channels, and professional forums. Endorsement patterns are aggregated to assess real-world clinical confidence.

Practitioner Insights

Who This Is For

✓ Great For

Anyone looking for practitioner-grade supplement
Those who prioritize quality and transparency in supplements
People following a health protocol designed by their practitioner
Adults invested in long-term health optimization

⚠ Important Notes

Always consult your healthcare provider before starting any supplement
Check for interactions with current medications
If pregnant or nursing, seek professional guidance first
Compare options using Apotheca's AI to find the best fit for your goals
Microbiome Labs is part of Gabriel's curated marketplace of practitioner-grade supplement brands. Every product from Microbiome Labs is evaluated across 50+ quality signals including manufacturing standards, ingredient sourcing, third-party testing, and clinical evidence.
Gabriel VerifiedQuality Analyzed

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Microbiome Labs
Microbiome Labs - ZenBiome Sleep
84
Strong Evidence
Gabriel Score
Strong quality signals. Meets recommended thresholds across most pillars.
Last updated: June 04, 2026
Score Breakdown
Manufacturing & GMP
96
Lab Verification
70
Review Consensus
77.7
Practitioner Confidence
58.0
Community & Social
61
Transparency
63
Consumer & Practitioner Intelligence
★★★☆☆ 3.9 from 63 reviews across 3 sources
Amazon 56Community 7+
Aggregated from verified purchases, practitioner clinical notes, and real-world outcome data
Scored across 50+ quality dimensions from 15+ independent databases. No brand can pay to influence their score. No sponsored rankings. Ever.
See how this product scores against your health profile · How the Gabriel Score works