Nutritional Frontiers

Progesterone 50 Cream (California Only), 3 oz

Nutritional Frontiers Progesterone 50 Cream is a topical progesterone formulation delivering 50 mg of bioidentical progesterone per measured dose through transdermal absorption.

May be a fit for

  • Adults seeking topical progesterone to support hormonal balance
  • Women in perimenopause looking to maintain progesterone levels
  • Those supporting a healthy estrogen-to-progesterone ratio topically
$89.99

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CreamFormat
3 ozPack size
The essentials

A closer look.

Nutritional Frontiers Progesterone 50 Cream is a topical progesterone formulation delivering 50 mg of bioidentical progesterone per measured dose through transdermal absorption. Designed to support hormonal balance, it may help maintain comfort during normal hormonal fluctuations for women seeking progesterone support. This product is available for sale in California only, in compliance with applicable state regulations.

Why It's Worth Considering: Transdermal delivery bypasses first-pass metabolism, offering an alternative absorption route to oral forms; the 50 mg dose per application provides a straightforward, measurable amount for consistent use.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking topical progesterone to support hormonal balance
  • Women in perimenopause looking to maintain progesterone levels
  • Those supporting a healthy estrogen-to-progesterone ratio topically
  • Individuals preferring transdermal progesterone over oral supplementation

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
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More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Nutritional Frontiers - Progesterone 50 Cream (California Only), 3 oz