Priority One

Hepa Cleanse, 60 Capsules

Hepa Cleanse by Priority One is a liver-support formula designed to support healthy hepatic function and detoxification pathways.

4.6 across 2 sources

May be a fit for

  • Adults seeking liver-supportive herbs like milk thistle and dandelion
  • Those looking to maintain healthy bile flow and gallbladder function
  • Individuals supporting detoxification pathways after dietary overindulgence
$29.99

30-day money-back guarantee
Save together with Wellness Circles

Invite friends or family to a Wellness Circle. Your group can unlock savings together. See current tiers and terms before joining.

Explore Wellness Circles
CapsulesFormat
60 CapsulesPack size
The essentials

A closer look.

Hepa Cleanse by Priority One is a liver-support formula designed to support healthy hepatic function and detoxification pathways. Combining botanical extracts and targeted nutrients, it is formulated for individuals seeking to support liver health, bile flow, and the body's natural phase I and phase II detox processes.

Why It's Worth Considering: Priority One's formulation draws on a practitioner-oriented approach, combining compounds commonly used in clinical settings to support liver cell integrity and antioxidant status.

The Apotheca perspective

50+ signals. A clearer standard.

Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.

67OUT OF 100
Manufacturing5757
Lab verification6565
Transparency5858

Our score is an editorial assessment, not a product certification or a guarantee of results.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking liver-supportive herbs like milk thistle and dandelion
  • Those looking to maintain healthy bile flow and gallbladder function
  • Individuals supporting detoxification pathways after dietary overindulgence
  • People seeking botanical compounds for healthy hepatic enzyme levels

Considerations

  • Fish/shellfish allergy (use algal omega-3 instead)
  • Taking blood thinners (consult physician — may enhance effect)
  • Scheduled surgery within 2 weeks (may increase bleeding)
  • Bleeding disorders
Compatibility & interactions

Works Well With

CoQ10
Both support cardiovascular health
Turmeric
Complementary anti-inflammatory pathways
Vitamin D3
Both fat-soluble, support immunity

Take Separately From

No significant interactions identified. Always consult your healthcare provider.

What to expect over time
Week 1–4

Cell Membrane Integration

EPA/DHA incorporate into cell membranes

Week 4–8

Inflammation Markers

Measurable CRP reduction

Month 2–3

Joint & Mood

Reduced joint stiffness, improved mood

Month 3–6

Cardiovascular

Triglycerides reduced 15-30%

Based on clinical research on EPA/DHA supplementation at therapeutic doses (2-4g combined EPA+DHA).

Compare the options

Compare Omega-3 Sources

Fish Oil vs Krill vs Algal vs Cod Liver

FeatureFish Oil (this)Krill OilAlgal OilCod Liver Oil
EPA+DHA ContentHigh (concentrated)ModerateModerate-HighModerate + Vit A/D
AbsorptionGood (triglyceride form)Excellent (phospholipid)GoodGood + fat-soluble vitamins
Best ForTherapeutic dose, heart/brainGeneral wellnessVegan optionVitamin A+D + omega-3
SustainabilityVaries by brandSustainable harvestMost sustainableTraditional, sustainable
Burp FactorLow (if enteric coated)Very lowNoneModerate
Explore complementary products
From across the web

Real reviews. A wider perspective.

Customer reviews, social conversations and expert insights, with every source in view.

4.6/5Aggregate source rating
Marketplaces & brand websites
Amazon, iHerb and direct brand reviews
Social & community
Reddit, X, Instagram and TikTok
Video & creators
YouTube and creator perspectives

Coverage varies by product and brand.

51 product and brand ratings and mentions across 2 sources.

Explore the source sentiment summary

Omega-3 benefits for depression, heart health, and longevity are widely cited, but contamination concerns and inconsistent product quality temper enthusiasm.

This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.

Good to know

A few useful answers.

Research & further reading

More category questions

How much fish oil should I take daily?

For general health, 1-2g of combined EPA+DHA daily. For therapeutic use (triglycerides, inflammation, mood), 2-4g combined EPA+DHA. Check the label for EPA+DHA content per serving — many fish oils have only 300mg per 1000mg capsule, requiring 6-8 capsules for a therapeutic dose. Concentrated formulas provide 600-900mg per capsule.

What is the difference between EPA and DHA?

EPA (eicosapentaenoic acid) is primarily anti-inflammatory — best for joint pain, cardiovascular health, and mood disorders. DHA (docosahexaenoic acid) is structural — it comprises 40% of brain polyunsaturated fats and is critical for cognitive function, eye health, and fetal development. Most people benefit from both; higher EPA for inflammation, higher DHA for brain health.

Does fish oil cause fishy burps?

Low-quality fish oil can cause fishy aftertaste and burping. Solutions: take with food, choose enteric-coated capsules, refrigerate the bottle (slows breakdown), or use a concentrated triglyceride-form fish oil (higher quality = less burping). If you still experience burps, the oil may be oxidized — check the expiration date and smell the capsule.

Is krill oil better than fish oil?

Krill oil has better absorption per gram (phospholipid form) and contains astaxanthin (antioxidant), but it's significantly more expensive per mg of EPA+DHA. For therapeutic doses (2-4g EPA+DHA), fish oil is more practical and cost-effective. Krill oil is a good choice for general wellness at maintenance doses.

Can I take fish oil with blood thinners?

Fish oil has mild blood-thinning properties. If you're taking warfarin, aspirin, or other anticoagulants, consult your physician before starting high-dose omega-3. At standard doses (1-2g), the risk is low, but your INR may need monitoring. Stop fish oil 1-2 weeks before scheduled surgery.

How do I choose a quality fish oil?

Look for: third-party tested for heavy metals and oxidation (IFOS 5-star rated), triglyceride form (not ethyl ester), high EPA+DHA per capsule (600mg+ combined), and molecular distillation for purity. The Gabriel Score evaluates all of these quality signals automatically.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Priority One - Hepa Cleanse, 60 Capsules Priority One

Apotheca quality score

67/100

The overall score combines several sources of information. The individual dimensions below show where those signals are stronger or more limited; they are not a simple average of the overall score.

Manufacturing5757
Lab verification6565
Review consensus5050
Practitioner signals45.045.0
Community signals6363
Transparency5858
See available brand signals
✓
Good manufacturing practices verifiedStandard
✓
Quality ingredients with verified sourcingGood
✓
Clean FDA regulatory recordNo issues
✓
Positive consumer reviews and community feedbackGood
✓
Authorized distribution channel verifiedDirect

Our score is an editorial assessment, not a product certification or a guarantee of results.

How our scoring works ↗