G.I. Integrity*, 120 Capsules
Pure Encapsulations G.I
May be a fit for
- Clinicians supporting intestinal lining integrity with glutamine-based protocols
- Adults seeking mucosal barrier support during periods of GI stress
- Practitioners addressing compromised gut permeability in sensitive patients
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Pure Encapsulations G.I. Integrity is a targeted gut-support formula combining L-glutamine, deglycyrrhizinated licorice (DGL), aloe vera, and zinc carnosine to support the structural integrity of the gastrointestinal lining. Formulated for individuals seeking comprehensive mucosal support, it addresses the nutritional needs of the intestinal epithelium through a multi-ingredient approach. This practitioner-grade product is free from common allergens and unnecessary excipients, consistent with Pure Encapsulations' manufacturing standards.
Why It's Worth Considering: The combination of zinc carnosine with L-glutamine and soothing botanicals offers a layered strategy for gut lining support that goes beyond single-ingredient formulas.
Pure Encapsulations · 120 CapsulesMake it part of your routine.
Take 4 capsules daily, in divided doses, with or between meals.
Read the complete labelProduct details
Supplement facts & complete label
Serving Size:
2 capsules
Amount Per Serving:
L-Glutamine (free-form) ... 1,000 mg
N-Acetyl-D-Glucosamine (from crab, shrimp) ... 500 mg
Gamma oryzanol (from rice bran) ... 150 mg
Aloe vera (Aloe barbadensis) extract (inner fillet) (standardized to contain 10% polysaccharides) ... 50 mg
Other Ingredients:
vegetarian capsule (cellulose, water)
Rare side effects of glucosamine or aloe include nausea, heartburn, diarrhea, constipation, drowsiness or headache. If pregnant or lactating, consult your physician before taking this product.
Individuals taking aloe and oral anti-hyperglycemic medications may require blood glucose monitoring. Consult your physician for more information.
*These statements have not been evaluated by the Food & Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
Label directions
Take 4 capsules daily, in divided doses, with or between meals.
Source: authorized supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Clinicians supporting intestinal lining integrity with glutamine-based protocols
- Adults seeking mucosal barrier support during periods of GI stress
- Practitioners addressing compromised gut permeability in sensitive patients
- Individuals using zinc carnosine and aloe to maintain digestive tract resilience
Considerations
- Known allergy to any ingredient (check label)
- Currently pregnant or breastfeeding (consult healthcare provider)
- Taking prescription medications (check for interactions)
- Under 18 years of age (unless recommended by pediatrician)
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Research & further reading
More category questions
How should I store this supplement?
Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.
Can I take this with other supplements?
Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.
How long should I take this supplement?
Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.
When is the best time to take this?
Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.
How do I know if this supplement is working?
Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.