Pure Encapsulations

Liposomal Glutathione, 60 Softgels

Size: 60 Softgel Capsules

4.6 across 7 sources

May be a fit for

  • Adults seeking enhanced cellular glutathione absorption via liposomal delivery
  • Practitioners supporting detoxification pathways with bioavailable liposomal glutathione
  • Individuals with higher oxidative stress demands needing sustained glutathione replenishment
$117.99

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SoftgelsFormat
60 SoftgelsPack size
The essentials

A closer look.

Pure Encapsulations Liposomal Glutathione delivers reduced glutathione encapsulated in phospholipid liposomes, a delivery form designed to support absorption and intracellular availability. Glutathione is the body's primary endogenous antioxidant, supporting cellular detoxification, oxidative stress response, and immune function. It's particularly relevant for those with higher oxidative demands or compromised antioxidant status.

Why It's Worth Considering: The liposomal encapsulation technology protects glutathione from degradation in the GI tract, a notable advantage over standard oral glutathione, which is poorly absorbed in unprotected form. Pure Encapsulations formulates to practitioner-grade standards with rigorous third-party testing.

The Apotheca perspective

50+ signals. A clearer standard.

Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.

98OUT OF 100
Manufacturing9898
Lab verification8383
Transparency7171

Our score is an editorial assessment, not a product certification or a guarantee of results.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking enhanced cellular glutathione absorption via liposomal delivery
  • Practitioners supporting detoxification pathways with bioavailable liposomal glutathione
  • Individuals with higher oxidative stress demands needing sustained glutathione replenishment
  • Those maintaining liver function who may benefit from liposomal glutathione supplementation

Considerations

  • Organ transplant recipients on immunosuppressants
  • Active chemotherapy (consult oncologist — may interfere)
  • Asthma (inhaled glutathione may trigger bronchospasm)
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From across the web

Real reviews. A wider perspective.

Customer reviews, social conversations and expert insights, with every source in view.

4.6/5Aggregate source rating
Marketplaces & brand websites
Amazon, iHerb and direct brand reviews
Social & community
Reddit, X, Instagram and TikTok
Video & creators
YouTube and creator perspectives

Coverage varies by product and brand.

1158 product and brand ratings and mentions across 7 sources.

Explore the source sentiment summary

Mixed consensus: glutathione praised for antioxidant and cognitive benefits, but Pure Encapsulations efficacy doubted and off-label use questioned.

This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.

Good to know

A few useful answers.

Research & further reading

More category questions

Is oral glutathione effective or do I need IV?

Standard oral glutathione is largely destroyed by stomach acid. Three forms that DO work orally: liposomal glutathione (lipid-wrapped, bypasses digestion), S-acetyl glutathione (acetyl group protects the molecule), and Setria glutathione (patented reduced form with clinical absorption data). IV glutathione is the most direct route but requires clinic visits.

What does glutathione do for the skin?

Glutathione inhibits tyrosinase (the enzyme that produces melanin), resulting in skin brightening and more even tone. It also neutralizes free radicals that cause premature aging. Clinical studies show 500mg/day of oral glutathione produces measurable skin lightening within 4-8 weeks. This is one of the most popular uses in Asia.

How much glutathione should I take?

For general antioxidant support: 250-500mg liposomal or S-acetyl form daily. For skin brightening: 500-1000mg daily. For liver support: 500mg 2x daily. For detoxification protocols: 1000-2000mg daily (often combined with NAC and ALA). Take on an empty stomach for best absorption.

Can I just take NAC instead of glutathione?

NAC is more cost-effective for raising INTRACELLULAR glutathione levels. Direct glutathione supplementation is better for immediate systemic antioxidant support and skin benefits. The ideal approach is both: NAC (600mg 2x/day) for sustained intracellular production + liposomal glutathione (500mg) for direct systemic availability.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Pure Encapsulations - Liposomal Glutathione, 60 Softgels Pure Encapsulations

Apotheca quality score

98/100

The overall score combines several sources of information. The individual dimensions below show where those signals are stronger or more limited; they are not a simple average of the overall score.

Manufacturing9898
Lab verification8383
Review consensus100100
Practitioner signals57.057.0
Community signals7171
Transparency7171
See available brand signals
✓
Third-party lab tested (heavy metals, contaminants)Pass
✓
GMP-certified manufacturing by Pure EncapsulationsCertified
✓
Premium ingredient sourcing with bioavailable formsHigh
✓
Clinical evidence available for primary ingredientsAvailable
✓
Clean FDA regulatory recordNo issues
✓
Positive consumer reviews and community feedbackGood
✓
Authorized distribution channel verifiedDirect

Our score is an editorial assessment, not a product certification or a guarantee of results.

How our scoring works ↗