M/R/S Mushroom Formula, 120 Capsules
Pure Encapsulations M/R/S Mushroom Formula combines maitake, reishi, and shiitake mushroom extracts in a single capsule designed to support immune function and overall wellness.
May be a fit for
- Practitioners formulating immune-modulating protocols with reishi, maitake, and shiitake extracts
- Adults seeking mushroom-derived beta-glucan support for everyday immune resilience
- Individuals supporting natural killer cell activity with adaptogenic mushroom compounds
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Pure Encapsulations M/R/S Mushroom Formula combines maitake, reishi, and shiitake mushroom extracts in a single capsule designed to support immune function and overall wellness. Formulated by a practitioner-grade brand known for rigorous testing and hypoallergenic manufacturing standards, this blend draws on three well-studied fungi with distinct bioactive profiles.
Why It's Worth Considering: Pure Encapsulations uses standardized mushroom extracts rather than raw powder, offering more consistent levels of key compounds like beta-glucans across batches.
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Pure Encapsulations · 120 CapsulesMake it part of your routine.
Take 1 capsule daily, with a meal, or as directed by a health professional.
Read the complete labelProduct details
Supplement facts & complete label
Serving Size:
1 capsule
Amount Per Serving:
Maitake mushroom (Grifola frondosa) extract (fruiting body) ... 200 mg
Reishi mushroom (Ganoderma lucidum) extract (fruiting body) ... 200 mg
Shiitake mushroom (Lentinus edodes) extract (fruiting body) ... 200 mg
Other Ingredients:
ascorbyl palmitate, vegetarian capsule (cellulose, water)
If pregnant or lactating, consult your physician before taking this product. Mild gastrointestinal upset, dry mouth and throat, dizziness, and nosebleeds have been reported in rare cases with the use of reishi mushroom.
Reishi mushroom extract is not recommended for those taking blood thinning medications. Consult your physician for more information.
Label directions
Take 1 capsule daily, with a meal, or as directed by a health professional.
Source: authorized supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Practitioners formulating immune-modulating protocols with reishi, maitake, and shiitake extracts
- Adults seeking mushroom-derived beta-glucan support for everyday immune resilience
- Individuals supporting natural killer cell activity with adaptogenic mushroom compounds
- Clinically-aware patients maintaining immune balance with a multi-mushroom extract blend
Considerations
- Mushroom allergy (rare but possible)
- Autoimmune conditions (mushroom beta-glucans stimulate immune activity)
- Taking immunosuppressants (may counteract medication)
- Bleeding disorders (Reishi has mild blood-thinning properties)
Compatibility & interactions
Works Well With
Take Separately From
No significant interactions identified. Always consult your healthcare provider.
What to expect over time
Immune Activation
Beta-glucans begin modulating immune cells
Cognitive Effects
NGF stimulation from Lion's Mane — improved focus
Sustained Benefits
Enhanced immune function and mental clarity
Full Adaptation
Neuroprotective and anti-inflammatory benefits established
Based on medicinal mushroom clinical research. Dual extraction (water + alcohol) provides the broadest spectrum of active compounds.
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Coverage varies by product and brand.
173 product and brand ratings and mentions across 4 sources.
These are broader practitioner and research perspectives. They may discuss the brand or other products, rather than this exact formula.
Explore the source sentiment summary
Pure Encapsulations is widely trusted by practitioners and health-conscious consumers for quality and bioavailable ingredients, though high pricing is a common concern.
This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.
A few useful answers.
Research & further reading
More category questions
What is the difference between fruiting body and mycelium?
Fruiting body is the actual mushroom cap/stem — it contains higher concentrations of beta-glucans, triterpenes, and active compounds. Mycelium is the root-like network that grows on grain substrate — products labeled 'mycelium on grain' may be 50-70% starch filler. For therapeutic use, always choose fruiting body extract or dual-extracted products.
Which mushroom supplement should I take?
Cognitive function: Lion's Mane (stimulates NGF for nerve growth). Immune support: Turkey Tail (highest beta-glucan content) or Chaga. Stress/sleep: Reishi (calming, adaptogenic). Energy: Cordyceps (ATP production). Cancer support: Turkey Tail (PSK/PSP research). Multi-purpose: a blend containing all five.
How should I take mushroom supplements?
Take with food for best absorption. Hot water extraction activates beta-glucans (the immune-active compounds). If using a powder, adding it to hot coffee or tea mimics the extraction process. Capsules of pre-extracted mushroom are ready to absorb. Dose varies by mushroom: Lion's Mane 500-1000mg, Reishi 1000-2000mg, Turkey Tail 1000-3000mg.
Are mushroom supplements safe to take daily?
Yes — medicinal mushrooms have thousands of years of traditional use and modern clinical evidence supporting daily consumption. They do not cause tolerance or dependence. Most people take them continuously as part of their daily supplement routine. The main caution is for those with autoimmune conditions or on immunosuppressants.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.