Magnesium (Glycinate), 180 Capsules
Pure Encapsulations Magnesium (Glycinate) delivers magnesium bound to glycine, a chelated form selected for its gastrointestinal tolerability compared to oxide or citrate forms.
May be a fit for
- Adults seeking magnesium glycinate for gentle, non-laxative daily magnesium repletion
- Practitioner protocols requiring highly bioavailable magnesium glycinate for sensitive GI patients
- Individuals using magnesium glycinate to support relaxation and restful sleep quality
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Pure Encapsulations Magnesium (Glycinate) delivers magnesium bound to glycine, a chelated form selected for its gastrointestinal tolerability compared to oxide or citrate forms. Magnesium supports muscle relaxation, nerve function, and healthy sleep patterns, making it a practical option for adults seeking foundational mineral support.
Why It's Worth Considering: Pure Encapsulations formulates without common excipients, artificial additives, or unnecessary fillers, reflecting the brand's practitioner-grade manufacturing standards. Magnesium glycinate is particularly well-suited for those who experience digestive sensitivity with other magnesium forms.
Pure Encapsulations · 180 CapsulesMake it part of your routine.
As a dietary supplement, take 1-4 capsules daily. Consume with food.
Read the complete labelProduct details
Supplement facts & complete label
Serving Size:
1 vegetarian capsule
Amount Per Serving:
Magnesium ... 120mg
(as magnesium glycinate)
Other Ingredients:
vegetarian capsule (cellulose, water), ascorbyl palmitate
STORAGE: Store in a cool, dry place.
WARNING: If you are pregnant or lactating, have any health condition, or are taking any medication, consult your health professional before use.
Label directions
As a dietary supplement, take 1-4 capsules daily. Consume with food.
Source: authorized supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking magnesium glycinate for gentle, non-laxative daily magnesium repletion
- Practitioner protocols requiring highly bioavailable magnesium glycinate for sensitive GI patients
- Individuals using magnesium glycinate to support relaxation and restful sleep quality
- Those with dietary gaps using magnesium glycinate to maintain healthy muscle function
Considerations
- Severe kidney disease (impaired Mg excretion)
- Taking antibiotics — separate by 2+ hours
- Myasthenia gravis
- Already taking high-dose magnesium from another source
Compatibility & interactions
Works Well With
Take Separately From
What to expect over time
Sleep Improvement
Faster sleep onset, deeper REM
Cramp Relief
Reduced nighttime cramps and muscle tension
Mood & Calm
Lower baseline anxiety, improved stress resilience
Serum Optimization
Measurable RBC magnesium improvement
Based on clinical research on magnesium supplementation. Effects are cumulative with consistent daily use.
Compare the options
Compare Magnesium Forms
Which form is right for you?
| Feature | Glycinate | Citrate | Oxide | L-Threonate | Taurate |
|---|---|---|---|---|---|
| Bioavailability | High (chelated) | Moderate-High | Low (4-5%) | Moderate | Moderate-High |
| Best For | Sleep, anxiety, cramps | Constipation, general | Budget (low absorption) | Cognitive function | Heart health |
| GI Tolerance | Excellent | Moderate | Poor (laxative) | Good | Good |
| Laxative Effect | None | Mild–Moderate | Strong | None | None |
| Evidence | Strong | Strong | Weak | Emerging | Moderate |
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A few useful answers.
Research & further reading
More category questions
What is the best form of magnesium to take?
Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.
Does magnesium glycinate cause diarrhea?
No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.
When is the best time to take magnesium?
Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works — glycinate does not require food for absorption.
How do I know if I am magnesium deficient?
Standard blood tests (serum magnesium) are unreliable — only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.
Can I take magnesium with other supplements?
Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.
How much magnesium should I take daily?
The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.