NAC + Glycine powder, 159 g
Pure Encapsulations NAC + Glycine Powder combines N-acetyl-L-cysteine and glycine, two precursors involved in glutathione synthesis, in a powdered, unflavored format designed for flexible dosing.
May be a fit for
- Adults seeking NAC and glycine to support glutathione synthesis
- Practitioners protocols requiring amino acid precursors for antioxidant pathways
- Individuals supporting liver detoxification with NAC in powder form
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Pure Encapsulations NAC + Glycine Powder combines N-acetyl-L-cysteine and glycine, two precursors involved in glutathione synthesis, in a powdered, unflavored format designed for flexible dosing. This formulation supports antioxidant activity and may help maintain healthy cellular defense mechanisms, making it well-suited for adults focused on oxidative stress management and recovery support.
Why It's Worth Considering: The powder format allows for precise, adjustable serving sizes and may support faster dissolution compared to capsules, a practical choice for those who prefer to blend supplements into beverages or for practitioners titrating doses for individual clients.
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Product details
Who it may suit
May be a fit for
- Adults seeking NAC and glycine to support glutathione synthesis
- Practitioners protocols requiring amino acid precursors for antioxidant pathways
- Individuals supporting liver detoxification with NAC in powder form
- Those with difficulty swallowing capsules needing NAC plus glycine delivery
Considerations
- Active bleeding or bleeding disorders
- Taking nitroglycerin (may cause hypotension)
- Asthma (rare cases of bronchospasm at high doses)
- Scheduled surgery within 1 week
What to expect over time
Glutathione Boost
Increased intracellular glutathione production
Liver Support
Enhanced phase II detoxification
Respiratory & Mental
Clearer breathing, reduced compulsive symptoms
Systemic Antioxidant
Reduced oxidative stress markers
Based on clinical NAC research at 600-1800mg/day.
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Thorne - Milk Thistle Phytosome (formerly Siliphos), 90 CapsulesNAC supports phase II liver detoxification while milk thistle (silymarin) protects liver cells from damage. The complete liver support stack.$48.99
NOW Foods - Selenium 200mcg, 180 CapsulesSelenium is required for glutathione peroxidase enzyme function. NAC + selenium maximizes the glutathione antioxidant pathway.$19.99Real reviews. A wider perspective.
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391 product and brand ratings and mentions across 5 sources.
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Explore the source sentiment summary
NAC shows strong support for respiratory, antioxidant, and hormonal benefits, but notable complaints about agitation, anxiety, and glycine sensitivity temper enthusiasm.
This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.
A few useful answers.
Research & further reading
More category questions
What is NAC used for?
NAC is the precursor to glutathione — the body's master antioxidant. It's used for liver detoxification, respiratory health (thins mucus), mental health (OCD, addiction, depression), immune support, and protecting against oxidative damage from toxins, alcohol, and environmental chemicals. It's also the standard ER treatment for acetaminophen overdose.
How much NAC should I take?
For general antioxidant support: 600mg 1-2x daily. For liver support: 1200-1800mg/day. For respiratory health: 600mg 2-3x daily. For mental health (OCD, addiction): 1200-2400mg/day (clinical study doses). Take on an empty stomach for best absorption.
Is NAC the same as glutathione?
No — NAC is a precursor that your body converts INTO glutathione. NAC has better oral bioavailability than direct glutathione supplements (which are largely destroyed in the stomach). NAC is generally more cost-effective for raising intracellular glutathione levels than oral glutathione, though liposomal glutathione is a viable alternative.
Can I take NAC every day?
Yes. NAC is well-tolerated for long-term daily use at standard doses (600-1800mg). It's water-soluble and excess is excreted. Common side effects are mild GI upset, which resolves by taking with food. There's no evidence of tolerance or need for cycling.
Does NAC help with hangovers?
NAC supports alcohol metabolism by boosting glutathione, which is depleted during alcohol detoxification. However, timing matters: take NAC BEFORE drinking (at least 30 minutes prior), not after. Taking NAC after alcohol may actually increase liver toxicity by interfering with the detoxification sequence.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.