Pure Encapsulations

NSK-SD 100mg, 60 Capsules

Pure Encapsulations NSK-SD is a 100mg nattokinase supplement derived from natto (fermented soybean) using a standardized, vitamin K-free extraction process.

4.6 across 4 sources

May be a fit for

  • Adults seeking NSK-SD nattokinase support for healthy circulation
  • Individuals looking to maintain normal fibrinolytic enzyme activity
  • Practitioners protocols requiring concentrated 100mg nattokinase dosing
$82.99

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CapsulesFormat
60 CapsulesPack size
The essentials

A closer look.

Pure Encapsulations NSK-SD is a 100mg nattokinase supplement derived from natto (fermented soybean) using a standardized, vitamin K-free extraction process. Nattokinase is a fibrinolytic enzyme studied for its role in supporting healthy circulation and normal blood flow. It's formulated for adults seeking cardiovascular and circulatory support without the complications of added vitamin K.

Why It's Worth Considering: NSK-SD is a clinically researched, standardized form of nattokinase with vitamin K removed, an important distinction for those monitoring vitamin K intake. Pure Encapsulations' hypoallergenic manufacturing aligns with practitioner-grade quality expectations.

The Apotheca perspective

50+ signals. A clearer standard.

Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.

84OUT OF 100
Manufacturing7878
Lab verification6565
Transparency5858

Our score is an editorial assessment, not a product certification or a guarantee of results.

Pure Encapsulations - NSK-SD 100mg, 60 CapsulesPure Encapsulations · 60 Capsules
Make it part of your day

Make it part of your routine.

As a dietary supplement, take 1 capsule 2 times daily, 12 hours apart, with or between meals.

Important cautions & interactions
Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Storage

Store in a cool, dry place.
Read the complete label
Inside the formula

Product details

Supplement facts & complete label

Supplement Facts — Serving size: 1 capsule.
NSK-SD® nattokinase (2,000 FU) (soy): 100 mg. Daily Value not established.
Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water), ascorbyl palmitate.
Contains soy.

Label directions

As a dietary supplement, take 1 capsule 2 times daily, 12 hours apart, with or between meals.

Label cautions

Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

Storage

Store in a cool, dry place.

Source: Pure Encapsulations manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.

Who it may suit

May be a fit for

  • Adults seeking NSK-SD nattokinase support for healthy circulation
  • Individuals looking to maintain normal fibrinolytic enzyme activity
  • Practitioners protocols requiring concentrated 100mg nattokinase dosing
  • Those supporting cardiovascular wellness with a fermented-soy-derived enzyme

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
From across the web

Real reviews. A wider perspective.

Customer reviews, social conversations and expert insights, with every source in view.

4.6/5Aggregate source rating
Marketplaces & brand websites
Amazon, iHerb and direct brand reviews
Social & community
Reddit, X, Instagram and TikTok
Video & creators
YouTube and creator perspectives

Coverage varies by product and brand.

348 product and brand ratings and mentions across 4 sources.

Explore the source sentiment summary

Pure Encapsulations is widely regarded as a high-quality, reputable supplement brand, though high prices are a common concern.

This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.

Good to know

A few useful answers.

Research & further reading

More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Pure Encapsulations - NSK-SD 100mg, 60 Capsules Pure Encapsulations

Apotheca quality score

84/100

The overall score combines several sources of information. The individual dimensions below show where those signals are stronger or more limited; they are not a simple average of the overall score.

Manufacturing7878
Lab verification6565
Review consensus97.497.4
Practitioner signals57.057.0
Community signals7171
Transparency5858
See available brand signals
✓
Good manufacturing practices verifiedStandard
✓
Quality ingredients with verified sourcingGood
✓
Clean FDA regulatory recordNo issues
✓
Positive consumer reviews and community feedbackGood
✓
Authorized distribution channel verifiedDirect

Our score is an editorial assessment, not a product certification or a guarantee of results.

How our scoring works ↗