Pure Encapsulations

PureGenomics® Ultramultivitamin, 90 Capsules

PureGenomics® Ultramultivitamin from Pure Encapsulations is a comprehensive multivitamin formulated with methylated B vitamins, including methylfolate (5-MTHF) and methylcobalamin, to support individuals with common MTHFR gene variants that may affect nutrient metabolism.

May be a fit for

  • Adults with MTHFR variants needing methylfolate-containing multivitamin support
  • Practitioners protocols requiring genotype-informed micronutrient formulations for patients
  • Individuals seeking activated B-vitamin forms like methylcobalamin and riboflavin-5-phosphate
$52.99

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CapsulesFormat
90 CapsulesPack size
The essentials

A closer look.

PureGenomics® Ultramultivitamin from Pure Encapsulations is a comprehensive multivitamin formulated with methylated B vitamins, including methylfolate (5-MTHF) and methylcobalamin, to support individuals with common MTHFR gene variants that may affect nutrient metabolism. Designed with genetic variability in mind, it provides activated, bioavailable forms of key micronutrients to support energy production, cognitive function, and overall cellular health.

Why It's Worth Considering: Unlike standard multivitamins, this formulation uses pre-converted, active nutrient forms, making it particularly relevant for those who don't efficiently convert synthetic folic acid or cyanocobalamin.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults with MTHFR variants needing methylfolate-containing multivitamin support
  • Practitioners protocols requiring genotype-informed micronutrient formulations for patients
  • Individuals seeking activated B-vitamin forms like methylcobalamin and riboflavin-5-phosphate
  • Those supporting methylation pathways with a comprehensive genomics-aligned multivitamin

Considerations

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)
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Good to know

A few useful answers.

Research & further reading

More category questions

How should I store this supplement?

Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.

Can I take this with other supplements?

Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

How long should I take this supplement?

Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

When is the best time to take this?

Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

How do I know if this supplement is working?

Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Pure Encapsulations - PureGenomics® Ultramultivitamin, 90 Capsules