Facts
Advanced Digestive Enzymes (formerly Bio-Gest)
Capsules · 180 capsules
- Adults seeking enzyme and betaine HCl support for protein breakdown
- Individuals supporting fat digestion with ox bile and lipase
- Those noticing occasional bloating after high-protein or fatty meals
- Brand Trust · 22% of verified reviews
Ingredients & product label
Serving Size:
Two Capsules
Amount Per Serving:
Betaine Hydrochloride ... 480 mg
L-Glutamic Acid Hydrochloride ... 480 mg
Pancreatin (Porcine)† ... 140 mg
Ox Bile concentrate ... 80 mg
Pepsin (Porcine) ... 70 mg
Other Ingredients:
Hypromellose (derived from cellulose), Leucine, Silicon Dioxide.
Gluten Free
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health professional before using this product.
INTERACTIONS
Bio-Gest should not be used concurrent with H2-blocking drugs and proton pump inhibitors because these drugs are intended to block the production of stomach HCl
ADDITIONAL WARNINGS
Bio-Gest is contraindicated in patients with peptic ulcers. It is not recommended to remove the Bio-Gest powder from the capsule to take orally, as it can be irritating to the oral mucosa.
Label directions
Take 1-2 capsules with each meal or as recommended by your health professional.
Open original label
Source: Fullscript supplier catalog · September 04, 2026. Formulas and labels can change. Check the packaging you receive.
About Thorne - Advanced Digestive Enzymes (formerly Bio-Gest)
Advanced Digestive Enzymes from Thorne is a comprehensive digestive support formula combining betaine HCl, pepsin, pancreatin, and ox bile extract to support the full breakdown of proteins, fats, and carbohydrates. Formerly sold as Bio-Gest, this capsule formulation is designed for adults who experience occasional digestive discomfort or those with lower gastric acid output who want broader digestive coverage.
Why It's Worth Considering: Thorne's practitioner-grade manufacturing standards and the combination of both upper and lower GI enzymes in a single capsule make this a well-rounded option compared to single-enzyme products.
Why Gabriel Recommends This
How to Take
Take 1-2 capsules with each meal or as recommended by your health professional.
Who Benefits
Best For
- Adults seeking enzyme and betaine HCl support for protein breakdown
- Individuals supporting fat digestion with ox bile and lipase
- Those noticing occasional bloating after high-protein or fatty meals
- Practitioner protocols requiring multi-enzyme coverage including protease and amylase
Cautions
- Active stomach or duodenal ulcers (especially betaine HCl)
- Taking blood thinners (some enzymes have mild anti-platelet activity)
- Active pancreatitis
Frequently Taken Together

Frequently Asked Questions
-
Take immediately before or with the first bites of your meal. Enzymes need to be in the stomach when food arrives. Taking them after eating is less effective. For best results, take with every substantial meal, especially meals high in fat, protein, or hard-to-digest foods.
-
They serve different functions. Enzymes physically break down food into absorbable nutrients. Probiotics are living bacteria that optimize the gut microbiome, produce vitamins, and support immune function. Many gut issues benefit from both, especially after age 40 when natural enzyme production declines.
-
No. Digestive enzymes do not cause your body to produce fewer of its own enzymes. They supplement what your body is already making (or under-making). You can stop taking them anytime without withdrawal or rebound. If your symptoms return after stopping, it means you still need the support, not that you've become dependent.
Real Reviews. Real Sources.
Compatibility Guide
Compatibility Data Loading
Apotheca is analyzing ingredient interactions, stacking compatibility, and timing recommendations for Thorne - Advanced Digestive Enzymes (formerly Bio-Gest). This data will be available soon.
Research Behind This
Practitioner Insights
Who This Is For
✓ Great For
⚠ Important Notes
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ask Gabriel
Want me to suggest complementary products, or do you have a specific health goal in mind?