Capsules · 60 capsules
Serving Size:
One Capsule
Amount Per Serving:
Vitamin C (as Ascorbic Acid) ... 15 mg
Vitamin B6 (as Pyridoxal 5’-Phosphate) ... 5 mg
Folate (400 mcg as L-5-Methyltetrahydrofolate† from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) ... 667 mcg DFE
Vitamin B12 (as Methylcobalamin) ... 300 mcg
Iron (as Ferrochel® Ferrous Bisglycinate Chelate)†† ... 36 mg
Other Ingredients:
Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Leucine, Silicon Dioxide.
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health professional before using this product.
INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
ADDITIONAL WARNINGS
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Take 1 capsule one to three times daily or as recommended by your health professional.
Open original label
Source: Fullscript supplier catalog · September 04, 2026. Formulas and labels can change. Check the packaging you receive.
Thorne's Advanced Iron Complex (formerly Ferrasorb) delivers iron bisglycinate chelate, a highly bioavailable, stomach-friendly form of iron, alongside folate (as 5-MTHF), vitamin B12, and vitamin C to support red blood cell formation and healthy iron status. Formulated for individuals with increased iron needs, including menstruating women, athletes, or those managing dietary gaps.
Why It's Worth Considering: The iron bisglycinate chelate form is gentler on the GI tract than ferrous sulfate, and pairing it with 5-MTHF and active B12 addresses the full nutritional picture for iron-deficiency-related fatigue support.
Take 1 capsule one to three times daily or as recommended by your health professional.
| Feature | Bisglycinate (gentle) | Ferrous Sulfate | Ferrous Fumarate | Heme Iron |
|---|---|---|---|---|
| Absorption | High (chelated) | Moderate | Moderate | Highest (animal-derived) |
| GI Side Effects | Minimal | Common (constipation) | Moderate | Minimal |
| Best For | Sensitive stomachs | Budget, proven | Higher elemental iron | Maximum absorption |
| Take With | Empty stomach OK | Vitamin C required | Vitamin C helps | Anytime |
Iron bisglycinate (Ferrochel) is the best-tolerated form with high absorption and minimal GI side effects. Ferrous sulfate is the most studied but commonly causes constipation and nausea. Heme iron polypeptide has the highest absorption rate but is animal-derived.
Non-chelated iron forms (ferrous sulfate, fumarate) are poorly absorbed, the unabsorbed iron irritates the gut lining and slows peristalsis. Chelated forms (bisglycinate) are absorbed more completely, leaving less unabsorbed iron in the gut. Taking vitamin C improves absorption and reduces GI side effects.
Separate iron from calcium, zinc, magnesium, and dairy by 2+ hours (they compete for absorption). Separate from thyroid medication by 4+ hours. DO take iron WITH vitamin C (doubles absorption). Avoid taking with coffee or tea (tannins reduce absorption by 60%).
Get a complete iron panel: serum ferritin (most sensitive, optimal is 50-100 ng/mL), serum iron, TIBC, and transferrin saturation. Symptoms of deficiency: fatigue, cold hands/feet, pale skin, brittle nails, shortness of breath, brain fog, and restless legs. Ferritin below 30 ng/mL warrants supplementation in most cases.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
