Grape Seed Extract (formerly O.P.C.-100), 60 Capsules
Size: 60 capsules
May be a fit for
- Adults seeking grape seed extract to support healthy vascular tone
- Individuals supporting antioxidant defenses against oxidative stress daily
- Practitioners protocols requiring oligomeric proanthocyanidins for circulatory wellness
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Thorne's Grape Seed Extract delivers a concentrated source of oligomeric proanthocyanidins (OPCs), the polyphenolic compounds derived from Vitis vinifera seed that support antioxidant defense and healthy vascular function. Formerly sold as O.P.C.-100, this formula is designed for those seeking plant-derived antioxidant support as part of a broader cardiovascular or oxidative stress wellness approach.
Why It's Worth Considering: Thorne is a practitioner-trusted brand known for rigorous raw material testing and manufacturing standards; this extract provides a standardized dose of OPCs in a clean capsule format without unnecessary excipients.
Thorne · 60 CapsulesMake it part of your routine.
Take 1 capsule 2–3 times daily or as recommended by your healthcare practitioner.
Important cautions & interactions
Product details
Supplement facts & complete label
Supplement Facts — Serving size: 1 capsule.
Grape Seed Phytosome (Vitis vinifera extract / phospholipid complex): 100 mg.
Other ingredients: microcrystalline cellulose, hypromellose (derived from cellulose) capsule, leucine, silicon dioxide. Contains an ingredient derived from soy (phytosome).
Label directions
Take 1 capsule 2–3 times daily or as recommended by your healthcare practitioner.
Label cautions
If pregnant, consult your healthcare practitioner before use. Use only if the bottle is sealed. Store tightly sealed in a cool, dry place.
Source: Thorne manufacturer label with iHerb label transcription · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking grape seed extract to support healthy vascular tone
- Individuals supporting antioxidant defenses against oxidative stress daily
- Practitioners protocols requiring oligomeric proanthocyanidins for circulatory wellness
- Those maintaining healthy collagen integrity and connective tissue resilience
Considerations
- Known allergy to any ingredient (check label)
- Currently pregnant or breastfeeding (consult healthcare provider)
- Taking prescription medications (check for interactions)
- Under 18 years of age (unless recommended by pediatrician)
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A few useful answers.
Research & further reading
More category questions
How should I store this supplement?
Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.
Can I take this with other supplements?
Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.
How long should I take this supplement?
Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.
When is the best time to take this?
Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.
How do I know if this supplement is working?
Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.