L-Arginine Plus (formerly Perfusia Plus), 180 Capsules
Size: 180 capsules
May be a fit for
- Adults seeking L-arginine support for healthy vascular tone
- Practitioners protocols requiring nitric oxide precursor amino acid support
- Individuals supporting cardiovascular circulation with L-arginine supplementation
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Thorne's L-Arginine Plus (formerly Perfusia Plus) delivers sustained-release L-arginine, an amino acid that serves as a precursor to nitric oxide and supports healthy vascular tone and circulation. Each capsule uses a time-release matrix designed to maintain steadier arginine availability compared to standard immediate-release forms. This is a practitioner-grade formulation from Thorne, a brand with a strong clinical reputation for manufacturing quality and ingredient integrity.
Why It's Worth Considering: The sustained-release delivery is a meaningful distinction, L-arginine is rapidly metabolized, so extended absorption may better support nitric oxide pathways over time. The 180-capsule count suits consistent, ongoing use.
Thorne · 180 CapsulesMake it part of your routine.
Take 3 capsules two times daily or as recommended by your health-care practitioner.
Important cautions & interactions
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health-care practitioner before using this product.
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity.
Individuals with a known herpes infection should not take L-arginine without also taking lysine, as L-arginine alone has been noted to cause herpes eruptions in susceptible individuals. L-arginine supplementation is contraindicated in a patient with hepatocellular carcinoma.
Product details
Supplement facts & complete label
Supplement Facts
Serving Size: 3 Capsules
Servings Per Container: 60
Folate (L-5-MTHF) 920mcg DFE
Green Tea Phytosome (decaffeinated / Phospholipid complex from Sunflower) 200mg
L-Arginine 1g
R-Lipoic Acid (Sodium) 50mg
Trans-Resveratrol 50mg
Vitamin C (as Ascorbic Acid) 300mg
Other Ingredients: High and Low Viscosity Hydroxypropyl Methylcellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide
Label directions
Take 3 capsules two times daily or as recommended by your health-care practitioner.
Label cautions
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health-care practitioner before using this product.
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity.
Individuals with a known herpes infection should not take L-arginine without also taking lysine, as L-arginine alone has been noted to cause herpes eruptions in susceptible individuals. L-arginine supplementation is contraindicated in a patient with hepatocellular carcinoma.
Source: Thorne manufacturer product label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking L-arginine support for healthy vascular tone
- Practitioners protocols requiring nitric oxide precursor amino acid support
- Individuals supporting cardiovascular circulation with L-arginine supplementation
- Active adults using L-arginine to maintain healthy blood flow during exercise
Considerations
- Known allergy to any ingredient (check label)
- Currently pregnant or breastfeeding (consult healthcare provider)
- Taking prescription medications (check for interactions)
- Under 18 years of age (unless recommended by pediatrician)
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A few useful answers.
Research & further reading
More category questions
How should I store this supplement?
Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements — some probiotics and oils require refrigeration.
Can I take this with other supplements?
Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.
How long should I take this supplement?
Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.
When is the best time to take this?
Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.
How do I know if this supplement is working?
Track your specific health goals — energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.