Thorne

L-Arginine Plus (formerly Perfusia Plus)

Capsules · 180 capsules

  • Adults seeking L-arginine support for healthy vascular tone
  • Practitioners protocols requiring nitric oxide precursor amino acid support
  • Individuals supporting cardiovascular circulation with L-arginine supplementation
  • Brand Trust · 22% of verified reviews
Quality & Trust Score
97 Strong Evidence
★★★★☆ 4.6 (716) 6 sources
See breakdown →
Manufacturing83
Lab Verification86
Review Consensus98.4
Brand-verified ·Good manufacturing practices verifiedQuality ingredients with verified sourcingClean FDA regulatory recordPositive consumer reviews and community feedbackAuthorized distribution channel verified
Referenced by  Chris Masterjohn, PhD & Integrativenp  →
$75.99
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Ingredients & product label

Supplement Facts
Serving Size: 3 Capsules
Servings Per Container: 60
Folate (L-5-MTHF) 920mcg DFE
Green Tea Phytosome (decaffeinated / Phospholipid complex from Sunflower) 200mg
L-Arginine 1g
R-Lipoic Acid (Sodium) 50mg
Trans-Resveratrol 50mg
Vitamin C (as Ascorbic Acid) 300mg
Other Ingredients: High and Low Viscosity Hydroxypropyl Methylcellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide

Label directions

Take 3 capsules two times daily or as recommended by your health-care practitioner.

Label cautions

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.



5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity.

Individuals with a known herpes infection should not take L-arginine without also taking lysine, as L-arginine alone has been noted to cause herpes eruptions in susceptible individuals. L-arginine supplementation is contraindicated in a patient with hepatocellular carcinoma.

Source: Thorne manufacturer product label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.

About Thorne - L-Arginine Plus (formerly Perfusia Plus)

Thorne's L-Arginine Plus (formerly Perfusia Plus) delivers sustained-release L-arginine, an amino acid that serves as a precursor to nitric oxide and supports healthy vascular tone and circulation. Each capsule uses a time-release matrix designed to maintain steadier arginine availability compared to standard immediate-release forms. This is a practitioner-grade formulation from Thorne, a brand with a strong clinical reputation for manufacturing quality and ingredient integrity.

Why It's Worth Considering: The sustained-release delivery is a meaningful distinction, L-arginine is rapidly metabolized, so extended absorption may better support nitric oxide pathways over time. The 180-capsule count suits consistent, ongoing use.

Compare & Learn
Pure Encapsulations vs Thorne

Why Gabriel Recommends This

Quality & Trust Score: 97 Strong Evidence
Quality Verified
Thorne products are evaluated across 50+ quality signals including manufacturing standards, lab verification, and ingredient sourcing transparency.
Label details
Ingredient amounts and serving sizes are shown in the product label section when supplier information is available.
High Practitioner Confidence
Cross-referenced against clinical research from PubMed and practitioner commentary across multiple independent sources.
Manufacturing Standards
Thorne maintains GMP-certified manufacturing. Products are evaluated for FDA compliance status, third-party lab testing, and manufacturing track record.
Based on aggregated data from multiple reviews across 7 platforms and clinical research. How the Quality & Trust Score works →
Recommendation generated by Gabriel AI based on publicly available practitioner commentary and quality data. Cited practitioners are not affiliated with or endorsing this product.

How to Take

Take 3 capsules two times daily or as recommended by your health-care practitioner.

Who Benefits

Best For

  • Adults seeking L-arginine support for healthy vascular tone
  • Practitioners protocols requiring nitric oxide precursor amino acid support
  • Individuals supporting cardiovascular circulation with L-arginine supplementation
  • Active adults using L-arginine to maintain healthy blood flow during exercise

Cautions

  • Known allergy to any ingredient (check label)
  • Currently pregnant or breastfeeding (consult healthcare provider)
  • Taking prescription medications (check for interactions)
  • Under 18 years of age (unless recommended by pediatrician)

Frequently Asked Questions

  • Store in a cool, dry place away from direct sunlight. Most supplements are stable at room temperature (59-77°F). Keep the bottle sealed between uses. Check the label for any specific storage requirements, some probiotics and oils require refrigeration.

  • Most supplements can be taken together safely. However, some minerals compete for absorption (zinc and iron, calcium and magnesium) and should be taken at different times of day. If you're taking prescription medications, consult your healthcare provider about potential interactions.

  • Most supplements benefit from consistent daily use over 2-3 months to achieve full effect. Some (like vitamins and minerals) can be taken indefinitely as part of a daily routine. Others (like specific herbs) may benefit from cycling. Follow the product's recommended protocol or consult a practitioner.

  • Fat-soluble supplements (vitamins A, D, E, K, omega-3, CoQ10) should be taken with a meal containing fat. Water-soluble supplements (B vitamins, vitamin C) can be taken anytime. Minerals are generally best absorbed with food. Probiotics should be taken with or just before a meal. Check the product label for specific timing recommendations.

  • Track your specific health goals, energy levels, sleep quality, joint comfort, digestion, mood, etc. Most supplements take 2-8 weeks for noticeable effects. For objective measurement, baseline lab tests before starting (and repeat at 3 months) provide definitive evidence. The Gabriel Score incorporates clinical evidence for expected outcomes.

Real Reviews. Real Sources.

4.6
716 reviews
5 star
75%
4 star
15%
3 star
5%
2 star
3%
1 star
2%
All (716)
0 Clinical Research
iHerb
0 iHerb
Amazon
618 Amazon
2 Practitioners
Reddit
48 Reddit
X
30 X
TikTok
1 TikTok
Instagram
17 Instagram
Substack
0 Substack
716 ratings aggregated across 6 sources · full-text reviews below
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Apotheca's Analysis · 50+ Signals Across 6 Dimensions
Sentiment is largely negative, dominated by concerns over PE acquisition, quality decline, COA refusals, and Amazon counterfeits; affiliate posts provide isolated positivity.
Brand Trust
22%
Quality
28%
Transparency
18%
Authenticity
20%
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Compatibility Guide

Compatibility Data Loading

Apotheca is analyzing ingredient interactions, stacking compatibility, and timing recommendations for Thorne - L-Arginine Plus (formerly Perfusia Plus). This data will be available soon.

Research Behind This

Thorne Product Quality Assessment
Quality & Trust Score Analysis
This product has been evaluated across 50+ quality signals including third-party testing, manufacturing standards, ingredient sourcing, and clinical evidence. Thorne products are analyzed against our comprehensive database of practitioner-grade supplements.
Practitioner Network Endorsement Data
Apotheca Practitioner Intelligence
Thorne is referenced across our practitioner network of clinical recommendations, YouTube health channels, and professional forums. Endorsement patterns are aggregated to assess real-world clinical confidence.

Practitioner Insights

Who This Is For

✓ Great For

Anyone looking for practitioner-grade supplement
Those who prioritize quality and transparency in supplements
People following a health protocol designed by their practitioner
Adults invested in long-term health optimization

⚠ Important Notes

Always consult your healthcare provider before starting any supplement
Check for interactions with current medications
If pregnant or nursing, seek professional guidance first
Compare options using Apotheca's AI to find the best fit for your goals
Thorne is part of Gabriel's curated marketplace of practitioner-grade supplement brands. Every product from Thorne is evaluated across 50+ quality signals including manufacturing standards, ingredient sourcing, third-party testing, and clinical evidence.
Gabriel VerifiedQuality Analyzed

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Thorne
Thorne - L-Arginine Plus (formerly Perfusia Plus)
97
Strong Evidence
Quality & Trust Score
Top-tier quality across all scoring pillars. Recommended with high confidence.
Last updated: September 08, 2026
Score Breakdown
Manufacturing & GMP
83
Lab Verification
86
Review Consensus
98.4
Practitioner Confidence
66.0
Community & Social
64
Transparency
75
Consumer & Practitioner Intelligence
★★★★☆ 4.6 from 716 reviews across 6 sources
Practitioner Data 2Amazon 618Community 96+
Aggregated from verified purchases, practitioner clinical notes, and real-world outcome data
Scored across 50+ quality dimensions from 15+ independent databases. No brand can pay to influence their score. No sponsored rankings. Ever.
See how this product scores against your health profile · How the Quality & Trust Score works