Magnesium Glycinate, 90 Capsules
Thorne Magnesium Glycinate delivers elemental magnesium bound to the amino acid glycine, a chelated form chosen for its gentle absorption and reduced laxative effect compared to magnesium oxide.
May be a fit for
- Adults seeking magnesium glycinate for relaxed, restful evening wind-down
- Individuals supporting healthy muscle recovery after regular physical training
- Those with practitioner-guided protocols requiring a well-tolerated magnesium form
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Thorne Magnesium Glycinate delivers elemental magnesium bound to the amino acid glycine, a chelated form chosen for its gentle absorption and reduced laxative effect compared to magnesium oxide. It supports muscle relaxation, healthy sleep patterns, and normal nerve function for adults seeking reliable daily magnesium repletion.
Why It's Worth Considering: Thorne's practitioner-grade manufacturing standards and use of the glycinate chelate make this a practical choice for those with sensitive digestion or who have found other magnesium forms poorly tolerated.
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Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.
Our score is an editorial assessment, not a product certification or a guarantee of results.
Thorne · 90 CapsulesMake it part of your routine.
Take 1 capsule one to four times daily or as recommended by your healthcare practitioner.
Important cautions & interactions
Product details
Supplement facts & complete label
Supplement Facts — Serving size: 1 capsule. Servings per container: 90.
Magnesium (as magnesium glycinate): 120 mg.
Other ingredients: hypromellose (derived from cellulose) capsule, medium chain triglyceride oil, silicon dioxide.
Label directions
Take 1 capsule one to four times daily or as recommended by your healthcare practitioner.
Label cautions
Contraindicated in individuals with a history of hypersensitivity to any ingredient. If pregnant, consult your healthcare practitioner before use. Gas, bloating or diarrhea may occur in some individuals taking magnesium supplements; this can occur at varying amounts depending on the individual and resolves when the amount is reduced.
Source: Thorne manufacturer product information · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking magnesium glycinate for relaxed, restful evening wind-down
- Individuals supporting healthy muscle recovery after regular physical training
- Those with practitioner-guided protocols requiring a well-tolerated magnesium form
- Adults maintaining magnesium levels without the digestive discomfort of oxide forms
Considerations
- Severe kidney disease (impaired Mg excretion)
- Taking antibiotics — separate by 2+ hours
- Myasthenia gravis
- Already taking high-dose magnesium from another source
Compatibility & interactions
Works Well With
Take Separately From
What to expect over time
Sleep Improvement
Faster sleep onset, deeper REM
Cramp Relief
Reduced nighttime cramps and muscle tension
Mood & Calm
Lower baseline anxiety, improved stress resilience
Serum Optimization
Measurable RBC magnesium improvement
Based on clinical research on magnesium supplementation. Effects are cumulative with consistent daily use.
Compare the options
Compare Magnesium Forms
Which form is right for you?
| Feature | Glycinate | Citrate | Oxide | L-Threonate | Taurate |
|---|---|---|---|---|---|
| Bioavailability | High (chelated) | Moderate-High | Low (4-5%) | Moderate | Moderate-High |
| Best For | Sleep, anxiety, cramps | Constipation, general | Budget (low absorption) | Cognitive function | Heart health |
| GI Tolerance | Excellent | Moderate | Poor (laxative) | Good | Good |
| Laxative Effect | None | Mild–Moderate | Strong | None | None |
| Evidence | Strong | Strong | Weak | Emerging | Moderate |
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1504 product and brand ratings and mentions across 8 sources.
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Explore the source sentiment summary
Overwhelmingly positive consensus that magnesium glycinate is a life-changing supplement, especially for sleep and overall wellbeing.
This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.
A few useful answers.
Research & further reading
More category questions
What is the best form of magnesium to take?
Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.
Does magnesium glycinate cause diarrhea?
No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.
When is the best time to take magnesium?
Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works — glycinate does not require food for absorption.
How do I know if I am magnesium deficient?
Standard blood tests (serum magnesium) are unreliable — only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.
Can I take magnesium with other supplements?
Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.
How much magnesium should I take daily?
The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.