Vital Nutrients

Magnesium (glycinate/malate), 200 Capsules

Vital Nutrients Magnesium (Glycinate/Malate) delivers magnesium in two well-absorbed, gentle forms, glycinate for relaxation and nervous system support, malate for energy metabolism and muscle comfort, making it suitable for adults seeking to maintain healthy magnesium levels without gastrointestinal....

May be a fit for

  • Adults seeking highly absorbable magnesium glycinate for relaxation support
  • Those using magnesium malate to help maintain healthy muscle function
  • Practitioners protocols requiring a dual-form magnesium with enhanced tolerability
$44.99

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CapsulesFormat
200 CapsulesPack size
The essentials

A closer look.

Vital Nutrients Magnesium (Glycinate/Malate) delivers magnesium in two well-absorbed, gentle forms, glycinate for relaxation and nervous system support, malate for energy metabolism and muscle comfort, making it suitable for adults seeking to maintain healthy magnesium levels without gastrointestinal discomfort.

Why It's Worth Considering: Vital Nutrients is a practitioner-grade brand formulating to pharmaceutical-grade standards; the glycinate/malate combination offers complementary mechanisms that single-form magnesium products often lack.

Inside the formula

Product details

Who it may suit

May be a fit for

  • Adults seeking highly absorbable magnesium glycinate for relaxation support
  • Those using magnesium malate to help maintain healthy muscle function
  • Practitioners protocols requiring a dual-form magnesium with enhanced tolerability
  • Individuals supporting restful sleep with chelated magnesium glycinate nightly

Considerations

  • Severe kidney disease (impaired Mg excretion)
  • Taking antibiotics — separate by 2+ hours
  • Myasthenia gravis
  • Already taking high-dose magnesium from another source
Compatibility & interactions

Works Well With

Vitamin D3
Mg activates vitamin D
B-Complex
Mg is a cofactor in B vitamin metabolism
Ashwagandha
Both support stress response

Take Separately From

Calcium
High-dose calcium can reduce Mg absorption
What to expect over time
Day 1–7

Sleep Improvement

Faster sleep onset, deeper REM

Week 2–4

Cramp Relief

Reduced nighttime cramps and muscle tension

Week 4–8

Mood & Calm

Lower baseline anxiety, improved stress resilience

Week 8–12

Serum Optimization

Measurable RBC magnesium improvement

Based on clinical research on magnesium supplementation. Effects are cumulative with consistent daily use.

Compare the options

Compare Magnesium Forms

Which form is right for you?

FeatureGlycinateCitrateOxideL-ThreonateTaurate
BioavailabilityHigh (chelated)Moderate-HighLow (4-5%)ModerateModerate-High
Best ForSleep, anxiety, crampsConstipation, generalBudget (low absorption)Cognitive functionHeart health
GI ToleranceExcellentModeratePoor (laxative)GoodGood
Laxative EffectNoneMild–ModerateStrongNoneNone
EvidenceStrongStrongWeakEmergingModerate
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Good to know

A few useful answers.

Research & further reading

More category questions

What is the best form of magnesium to take?

Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.

Does magnesium glycinate cause diarrhea?

No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.

When is the best time to take magnesium?

Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works — glycinate does not require food for absorption.

How do I know if I am magnesium deficient?

Standard blood tests (serum magnesium) are unreliable — only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.

Can I take magnesium with other supplements?

Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.

How much magnesium should I take daily?

The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.

Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.

Vital Nutrients - Magnesium (glycinate/malate), 200 Capsules