OptiMag 125 (Magnesium), 240 Capsules
OptiMag 125 by Xymogen delivers 125 mg of magnesium as magnesium glycinate lysinate chelate (TRAACS®), a form designed for enhanced absorption and gastrointestinal tolerability compared to magnesium oxide or citrate.
May be a fit for
- Adults seeking magnesium glycinate to support restful, uninterrupted sleep
- Practitioners protocols requiring highly bioavailable magnesium for muscle relaxation support
- Individuals supporting healthy stress responses with well-tolerated magnesium glycinate
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OptiMag 125 by Xymogen delivers 125 mg of magnesium as magnesium glycinate lysinate chelate (TRAACS®), a form designed for enhanced absorption and gastrointestinal tolerability compared to magnesium oxide or citrate. This practitioner-grade formula supports muscle relaxation, healthy nervous system function, and may help maintain normal sleep quality and stress response. Well-suited for adults seeking a highly bioavailable magnesium option.
Why It's Worth Considering: The TRAACS® chelated form uses Albion Minerals' patented process, binding magnesium to amino acids for superior cellular uptake, a meaningful distinction from lower-cost inorganic forms commonly found in mainstream supplements.
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Product details
Who it may suit
May be a fit for
- Adults seeking magnesium glycinate to support restful, uninterrupted sleep
- Practitioners protocols requiring highly bioavailable magnesium for muscle relaxation support
- Individuals supporting healthy stress responses with well-tolerated magnesium glycinate
- Those maintaining normal magnesium levels with a gentle, non-laxative magnesium form
Considerations
- Severe kidney disease (impaired Mg excretion)
- Taking antibiotics — separate by 2+ hours
- Myasthenia gravis
- Already taking high-dose magnesium from another source
Compatibility & interactions
Works Well With
Take Separately From
What to expect over time
Sleep Improvement
Faster sleep onset, deeper REM
Cramp Relief
Reduced nighttime cramps and muscle tension
Mood & Calm
Lower baseline anxiety, improved stress resilience
Serum Optimization
Measurable RBC magnesium improvement
Based on clinical research on magnesium supplementation. Effects are cumulative with consistent daily use.
Compare the options
Compare Magnesium Forms
Which form is right for you?
| Feature | Glycinate | Citrate | Oxide | L-Threonate | Taurate |
|---|---|---|---|---|---|
| Bioavailability | High (chelated) | Moderate-High | Low (4-5%) | Moderate | Moderate-High |
| Best For | Sleep, anxiety, cramps | Constipation, general | Budget (low absorption) | Cognitive function | Heart health |
| GI Tolerance | Excellent | Moderate | Poor (laxative) | Good | Good |
| Laxative Effect | None | Mild–Moderate | Strong | None | None |
| Evidence | Strong | Strong | Weak | Emerging | Moderate |
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Coverage varies by product and brand.
344 product and brand ratings and mentions across 4 sources.
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Explore the source sentiment summary
Magnesium supplementation is widely praised for sleep, mood, and energy improvements, with glycinate and threonate forms most recommended.
This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.
A few useful answers.
Research & further reading
More category questions
What is the best form of magnesium to take?
Magnesium glycinate (bisglycinate chelate) is widely considered the best form for sleep, anxiety, and muscle cramps due to high bioavailability and zero laxative effect. Citrate is better for constipation. Threonate may be superior for cognitive function as it crosses the blood-brain barrier. Oxide has only 4-5% absorption and is primarily a laxative.
Does magnesium glycinate cause diarrhea?
No. Unlike magnesium citrate and oxide which draw water into the intestines (osmotic laxative effect), glycinate is chelated and absorbed through a different pathway that does not affect GI motility. It is the most GI-friendly magnesium form available.
When is the best time to take magnesium?
Take 1-2 hours before bed for sleep benefits. The glycine component promotes relaxation via GABA receptor activity. For general supplementation, any time works — glycinate does not require food for absorption.
How do I know if I am magnesium deficient?
Standard blood tests (serum magnesium) are unreliable — only 1% of body magnesium is in the blood. Signs include muscle cramps, poor sleep, anxiety, eye twitches, chocolate cravings, and headaches. Since 80%+ of adults are suboptimal, supplementation is generally recommended.
Can I take magnesium with other supplements?
Yes, but separate from zinc, calcium, and iron by 2+ hours (they compete for absorption). Magnesium pairs well with Vitamin D3, K2, and B6 taken together.
How much magnesium should I take daily?
The RDA is 310-420mg/day for adults. Most functional medicine practitioners recommend 400-600mg for therapeutic benefit. Start with the product's recommended dose and adjust based on response.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.