Capsules · 60 capsules
Serving Size:
2 Vegetable Capsule
Amount Per Serving:
Prebiotic Blend … 440 mg
Fermented Astragalus (Astragalus propinquus; Root)†
Fermented Jerusalem Artichoke (Whole Plant; Helianthus tuberosus)†
Fermented Acacia Fiber†
Fermented Turkey Tail Mushroom (Fruiting Bodies; Trametes versicolor)†
Fermented Holy Basil Leaf (Ocimum tenuiflorum)†
Fermented Sprouted Broccoli Seed†
Probiotic Blend (50B CFU‡) … 143 mg
L. plantarum
L. paracasei
B. subtilis
B. clausii
B. coagulans
S. boulardii
Other Ingredients:
Methylcellulose Capsule
Take 2 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.
Do not exceed recommended dose. Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Please use caution if you have allergies or sensitivities to any of the listed ingredients.
Source: Fullscript original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Amen SBO Probiotic delivers 50 billion CFU of soil-based organisms (SBOs) per capsule, a distinct class of probiotics naturally adapted to survive harsh digestive conditions without refrigeration. SBO strains are selected for their resilience and may help support gut microbiome balance, digestive comfort, and immune function. Well-suited for adults who haven't responded to conventional lactobacillus-based probiotics or who want a more shelf-stable option.
Why It's Worth Considering: Soil-based organisms form protective endospores, giving them a survival advantage through the GI tract that many standard strains lack, no cold chain required.
Take 2 capsules daily with 8 ounces of water or your favorite beverage. May be taken with or without food.
| Feature | Multi-Strain (this) | Spore-Based | Saccharomyces | Single-Strain |
|---|---|---|---|---|
| Survivability | Moderate (refrigerate) | Excellent (shelf-stable) | Excellent (yeast-based) | Moderate |
| Best For | General gut health | Antibiotic recovery | Diarrhea, C. diff | Targeted conditions |
| CFU Range | 10-100 billion | 2-5 billion (potent) | 5-10 billion | 1-50 billion |
| Research | Extensive | Growing | Strong (S. boulardii) | Strain-specific |
For general health maintenance, 10-20 billion CFU is sufficient. For therapeutic use (post-antibiotics, IBS, immune support), 50-100 billion CFU is recommended. More important than CFU count is strain diversity and survivability, a 5 billion spore-based probiotic may be more effective than a 100 billion conventional strain that doesn't survive stomach acid.
Take with food or within 30 minutes of eating. Food buffers stomach acid and increases probiotic survival by up to 100x. A small amount of fat in the meal further improves survival. Exception: spore-based probiotics (Bacillus strains) are acid-resistant and can be taken anytime.
Yes, temporary bloating, gas, or changes in bowel habits during the first 3-7 days is common and actually a positive sign. This 'die-off' reaction occurs as beneficial bacteria displace harmful organisms. If symptoms persist beyond 2 weeks, reduce the dose by half and gradually increase.
It depends on the strain. Most Lactobacillus and Bifidobacterium strains require refrigeration for viability. Spore-based probiotics (Bacillus) and Saccharomyces boulardii are shelf-stable. Check the label, if it says 'viable at time of manufacture' rather than 'at time of expiration,' refrigerate.
Yes, in fact, it's strongly recommended. Take the probiotic 2-3 hours apart from the antibiotic dose (so the antibiotic doesn't kill the probiotic). Saccharomyces boulardii is particularly resistant to antibiotics. Continue probiotics for at least 2-4 weeks after completing the antibiotic course.
For acute use (post-antibiotics, traveler's diarrhea), 4-8 weeks minimum. For chronic conditions (IBS, immune support), ongoing daily use is recommended. Probiotics don't permanently colonize, they exert benefits while you take them and for a limited time after stopping. Think of them as a daily maintenance supplement, not a one-time fix.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
