SBO Probiotic Gut Restore, 60 Capsules
60 Capsules
May be a fit for
- Adults seeking soil-based organism probiotics for digestive balance
- Those supporting gut lining integrity with SBO probiotic strains
- Individuals transitioning to ancestral-aligned microbiome support
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Ancient Nutrition SBO Probiotic Gut Restore delivers soil-based organisms (SBOs), a category of hardy, spore-forming bacteria naturally found in the earth, formulated to support digestive balance, gut lining integrity, and a healthy microbiome environment. SBOs are recognized for their resilience through the digestive tract compared to conventional probiotic strains, making this a consideration for adults seeking a more robust delivery format.
Why It's Worth Considering: The soil-based organism format offers stability without refrigeration, and Ancient Nutrition combines these strains with a blend of fermented botanicals and prebiotics intended to support the probiotic environment.
Ancient Nutrition · 60 CapsulesMake it part of your routine.
Adults take 2 capsules daily with 8 ounces of water We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed Not intended for children
Important cautions & interactions
Keep out of reach of children.
Product details
Supplement facts & complete label
Serving Size:
2 Capsules
Amount Per Serving:
Magnesium ... 9 mg
Zinc ... 20 mg
SBO Gut Restore† Probiotic Blend ... 621 mg (25 Billion CFU¹)
(Saccharomyces boulardii, Bacillus coagulans, Bacillus clausii, Bacillus subtilis)
Organic Gut Restore† Blend ... 170 mg
(Organic Fermented Licorice Root, Organic Fermented Marshmallow Root, L-glutamine)
Organic Mushroom Blend ... 140 mg
(Organic Turkey Tail (Trametes versicolor) Mycelium, Organic Shiitake Mycelium, Organic Reishi Mycelium, Organic Maitake (Grifola frondosa) Mycelium)
Other Ingredients:
Hypromellose
Does not contain: Gluten, Nuts, Dairy.
Label directions
Adults take 2 capsules daily with 8 ounces of water We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed Not intended for children
Label cautions
Warning: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing or otherwise under medical supervision. Store in a cool, dry place. Do not use if product has been opened or tampered with in any way.
Keep out of reach of children.
Source: authorized supplier original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking soil-based organism probiotics for digestive balance
- Those supporting gut lining integrity with SBO probiotic strains
- Individuals transitioning to ancestral-aligned microbiome support
- People maintaining bowel regularity with spore-forming probiotic cultures
Considerations
- Severely immunocompromised (consult physician)
- Active pancreatitis
- Central venous catheters (risk of translocation)
- SIBO (some probiotics may worsen — consult practitioner)
Compatibility & interactions
Works Well With
Take Separately From
No significant interactions identified. Always consult your healthcare provider.
What to expect over time
Colonization Begins
Beneficial bacteria begin establishing colonies
GI Improvement
Reduced bloating, improved regularity
Immune Modulation
Enhanced immune markers, fewer infections
Microbiome Shift
Sustained diversity improvement
Based on clinical probiotic research. Initial die-off symptoms (temporary bloating) may occur in the first week.
Compare the options
Compare Probiotic Types
Which strain type is right for you?
| Feature | Multi-Strain (this) | Spore-Based | Saccharomyces | Single-Strain |
|---|---|---|---|---|
| Survivability | Moderate (refrigerate) | Excellent (shelf-stable) | Excellent (yeast-based) | Moderate |
| Best For | General gut health | Antibiotic recovery | Diarrhea, C. diff | Targeted conditions |
| CFU Range | 10-100 billion | 2-5 billion (potent) | 5-10 billion | 1-50 billion |
| Research | Extensive | Growing | Strong (S. boulardii) | Strain-specific |
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These are broader practitioner and research perspectives. They may discuss the brand or other products, rather than this exact formula.
A few useful answers.
Research & further reading
More category questions
How many CFU do I need in a probiotic?
For general health maintenance, 10-20 billion CFU is sufficient. For therapeutic use (post-antibiotics, IBS, immune support), 50-100 billion CFU is recommended. More important than CFU count is strain diversity and survivability — a 5 billion spore-based probiotic may be more effective than a 100 billion conventional strain that doesn't survive stomach acid.
Should I take probiotics with food or on an empty stomach?
Take with food or within 30 minutes of eating. Food buffers stomach acid and increases probiotic survival by up to 100x. A small amount of fat in the meal further improves survival. Exception: spore-based probiotics (Bacillus strains) are acid-resistant and can be taken anytime.
Can probiotics cause bloating at first?
Yes — temporary bloating, gas, or changes in bowel habits during the first 3-7 days is common and actually a positive sign. This 'die-off' reaction occurs as beneficial bacteria displace harmful organisms. If symptoms persist beyond 2 weeks, reduce the dose by half and gradually increase.
Do I need to refrigerate probiotics?
It depends on the strain. Most Lactobacillus and Bifidobacterium strains require refrigeration for viability. Spore-based probiotics (Bacillus) and Saccharomyces boulardii are shelf-stable. Check the label — if it says 'viable at time of manufacture' rather than 'at time of expiration,' refrigerate.
Can I take probiotics with antibiotics?
Yes — in fact, it's strongly recommended. Take the probiotic 2-3 hours apart from the antibiotic dose (so the antibiotic doesn't kill the probiotic). Saccharomyces boulardii is particularly resistant to antibiotics. Continue probiotics for at least 2-4 weeks after completing the antibiotic course.
How long should I take probiotics?
For acute use (post-antibiotics, traveler's diarrhea), 4-8 weeks minimum. For chronic conditions (IBS, immune support), ongoing daily use is recommended. Probiotics don't permanently colonize — they exert benefits while you take them and for a limited time after stopping. Think of them as a daily maintenance supplement, not a one-time fix.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.