Capsules · 60 capsules
Serving Size:
2 Capsules
Amount Per Serving:
Magnesium ... 9 mg
Zinc ... 20 mg
SBO Gut Restore† Probiotic Blend ... 621 mg (25 Billion CFU¹)
(Saccharomyces boulardii, Bacillus coagulans, Bacillus clausii, Bacillus subtilis)
Organic Gut Restore† Blend ... 170 mg
(Organic Fermented Licorice Root, Organic Fermented Marshmallow Root, L-glutamine)
Organic Mushroom Blend ... 140 mg
(Organic Turkey Tail (Trametes versicolor) Mycelium, Organic Shiitake Mycelium, Organic Reishi Mycelium, Organic Maitake (Grifola frondosa) Mycelium)
Other Ingredients:
Hypromellose
Does not contain: Gluten, Nuts, Dairy.
Adults take 2 capsules daily with 8 ounces of water We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed Not intended for children
Warning: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing or otherwise under medical supervision. Store in a cool, dry place. Do not use if product has been opened or tampered with in any way.
Keep out of reach of children.
Source: Fullscript original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Ancient Nutrition SBO Probiotic Gut Restore delivers soil-based organisms (SBOs), a category of hardy, spore-forming bacteria naturally found in the earth, formulated to support digestive balance, gut lining integrity, and a healthy microbiome environment. SBOs are recognized for their resilience through the digestive tract compared to conventional probiotic strains, making this a consideration for adults seeking a more robust delivery format.
Why It's Worth Considering: The soil-based organism format offers stability without refrigeration, and Ancient Nutrition combines these strains with a blend of fermented botanicals and prebiotics intended to support the probiotic environment.
Adults take 2 capsules daily with 8 ounces of water We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed Not intended for children
| Feature | Multi-Strain (this) | Spore-Based | Saccharomyces | Single-Strain |
|---|---|---|---|---|
| Survivability | Moderate (refrigerate) | Excellent (shelf-stable) | Excellent (yeast-based) | Moderate |
| Best For | General gut health | Antibiotic recovery | Diarrhea, C. diff | Targeted conditions |
| CFU Range | 10-100 billion | 2-5 billion (potent) | 5-10 billion | 1-50 billion |
| Research | Extensive | Growing | Strong (S. boulardii) | Strain-specific |
For general health maintenance, 10-20 billion CFU is sufficient. For therapeutic use (post-antibiotics, IBS, immune support), 50-100 billion CFU is recommended. More important than CFU count is strain diversity and survivability, a 5 billion spore-based probiotic may be more effective than a 100 billion conventional strain that doesn't survive stomach acid.
Take with food or within 30 minutes of eating. Food buffers stomach acid and increases probiotic survival by up to 100x. A small amount of fat in the meal further improves survival. Exception: spore-based probiotics (Bacillus strains) are acid-resistant and can be taken anytime.
Yes, temporary bloating, gas, or changes in bowel habits during the first 3-7 days is common and actually a positive sign. This 'die-off' reaction occurs as beneficial bacteria displace harmful organisms. If symptoms persist beyond 2 weeks, reduce the dose by half and gradually increase.
It depends on the strain. Most Lactobacillus and Bifidobacterium strains require refrigeration for viability. Spore-based probiotics (Bacillus) and Saccharomyces boulardii are shelf-stable. Check the label, if it says 'viable at time of manufacture' rather than 'at time of expiration,' refrigerate.
Yes, in fact, it's strongly recommended. Take the probiotic 2-3 hours apart from the antibiotic dose (so the antibiotic doesn't kill the probiotic). Saccharomyces boulardii is particularly resistant to antibiotics. Continue probiotics for at least 2-4 weeks after completing the antibiotic course.
For acute use (post-antibiotics, traveler's diarrhea), 4-8 weeks minimum. For chronic conditions (IBS, immune support), ongoing daily use is recommended. Probiotics don't permanently colonize, they exert benefits while you take them and for a limited time after stopping. Think of them as a daily maintenance supplement, not a one-time fix.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
