Capsules · 60 capsules
Serving Size:
2 Capsules
Amount Per Serving:
SBO Ultimate Probiotic Blend ... 808 mg (50 Billion CFU¹)
(Saccharomyces boulardii, Bacillus coagulans, Bacillus subtilis, Bacillus clausii)
Organic Fermented Botanical Blend ... 350 mg
(Organic Fermented Black Pepper Fruit, Organic Fermented Ginger Root, Organic Fermented Turmeric Root)
Other Ingredients:
Hypromellose
Contains no filler ingredients, artificial flavors, colors, sweeteners or preservatives.
As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing or otherwise under medical supervision. Store in a cool, dry place. Do not use if product has been opened or tampered with in any way. Keep out of reach of children.
Adults take 2 capsules daily with 8 ounces of water
We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed
Not intended for children
Source: Fullscript original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Ancient Nutrition SBO Probiotic Ultimate is a soil-based organism (SBO) probiotic formula delivering a blend of spore-forming and humic/fulvic acid-supported bacteria strains designed to support gut microbiome balance, digestive comfort, and immune function. It's formulated for adults who prefer a hardier probiotic strain profile that may survive the digestive tract more robustly than traditional lactobacillus-only formulas.
Why It's Worth Considering: The SBO (soil-based organism) delivery format uses spore-forming strains paired with humic and fulvic acids, which may support survivability through stomach acid and colonization in the gut environment.
Adults take 2 capsules daily with 8 ounces of water
We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed
Not intended for children
| Feature | Multi-Strain (this) | Spore-Based | Saccharomyces | Single-Strain |
|---|---|---|---|---|
| Survivability | Moderate (refrigerate) | Excellent (shelf-stable) | Excellent (yeast-based) | Moderate |
| Best For | General gut health | Antibiotic recovery | Diarrhea, C. diff | Targeted conditions |
| CFU Range | 10-100 billion | 2-5 billion (potent) | 5-10 billion | 1-50 billion |
| Research | Extensive | Growing | Strong (S. boulardii) | Strain-specific |
For general health maintenance, 10-20 billion CFU is sufficient. For therapeutic use (post-antibiotics, IBS, immune support), 50-100 billion CFU is recommended. More important than CFU count is strain diversity and survivability, a 5 billion spore-based probiotic may be more effective than a 100 billion conventional strain that doesn't survive stomach acid.
Take with food or within 30 minutes of eating. Food buffers stomach acid and increases probiotic survival by up to 100x. A small amount of fat in the meal further improves survival. Exception: spore-based probiotics (Bacillus strains) are acid-resistant and can be taken anytime.
Yes, temporary bloating, gas, or changes in bowel habits during the first 3-7 days is common and actually a positive sign. This 'die-off' reaction occurs as beneficial bacteria displace harmful organisms. If symptoms persist beyond 2 weeks, reduce the dose by half and gradually increase.
It depends on the strain. Most Lactobacillus and Bifidobacterium strains require refrigeration for viability. Spore-based probiotics (Bacillus) and Saccharomyces boulardii are shelf-stable. Check the label, if it says 'viable at time of manufacture' rather than 'at time of expiration,' refrigerate.
Yes, in fact, it's strongly recommended. Take the probiotic 2-3 hours apart from the antibiotic dose (so the antibiotic doesn't kill the probiotic). Saccharomyces boulardii is particularly resistant to antibiotics. Continue probiotics for at least 2-4 weeks after completing the antibiotic course.
For acute use (post-antibiotics, traveler's diarrhea), 4-8 weeks minimum. For chronic conditions (IBS, immune support), ongoing daily use is recommended. Probiotics don't permanently colonize, they exert benefits while you take them and for a limited time after stopping. Think of them as a daily maintenance supplement, not a one-time fix.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
