Capsules · 60 capsules
Serving Size:
2 Capsules
Amount Per Serving:
Zinc ... 15 mg
Selenium ... 100 mcg
SBO Men’s Probiotic Blend ... 621 mg (25 Billion CFU¹)
(Saccharomyces boulardii, Bacillus coagulans, Bacillus clausii, Bacillus subtilis)
Organic Fermented Botanical Blend ... 480 mg
(Organic Fermented Ginger Root, Organic Fermented Fenugreek Seed, Organic Fermented Fo-Ti Root.)
Organic Mushroom Blend ... 75 mg
(Organic Turkey Tail (Trametes versicolor) Mycelium, Organic Shiitake Mycelium, Organic Reishi Mycelium, Organic Maitake (Grifola frondosa) Mycelium)
Other Ingredients:
Hypromellose.
Does not contain: Gluten, Nuts, Dairy.
Adults take two capsules daily with 8 ounces of water We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed Not intended for children.
Warning: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing or under medical supervision. If you are currently undergoing HIV treatment, chemotherapy, or allograft therapy, do not use before consulting your physician.
Source: Fullscript original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Ancient Nutrition SBO Probiotics Men's is a soil-based organism (SBO) probiotic formula designed to support digestive balance, immune function, and overall gut health in men. SBOs are hardy, spore-forming strains that are naturally resistant to heat and stomach acid, allowing them to reach the intestinal tract intact.
Why It's Worth Considering: The SBO delivery format offers stability advantages over conventional strains, and this men's formulation pairs probiotic strains with a prebiotic blend and botanicals relevant to male wellness.
Adults take two capsules daily with 8 ounces of water We recommend taking the capsules on an empty stomach, either when you first wake up or right before bed Not intended for children.
| Feature | Multi-Strain (this) | Spore-Based | Saccharomyces | Single-Strain |
|---|---|---|---|---|
| Survivability | Moderate (refrigerate) | Excellent (shelf-stable) | Excellent (yeast-based) | Moderate |
| Best For | General gut health | Antibiotic recovery | Diarrhea, C. diff | Targeted conditions |
| CFU Range | 10-100 billion | 2-5 billion (potent) | 5-10 billion | 1-50 billion |
| Research | Extensive | Growing | Strong (S. boulardii) | Strain-specific |
For general health maintenance, 10-20 billion CFU is sufficient. For therapeutic use (post-antibiotics, IBS, immune support), 50-100 billion CFU is recommended. More important than CFU count is strain diversity and survivability, a 5 billion spore-based probiotic may be more effective than a 100 billion conventional strain that doesn't survive stomach acid.
Take with food or within 30 minutes of eating. Food buffers stomach acid and increases probiotic survival by up to 100x. A small amount of fat in the meal further improves survival. Exception: spore-based probiotics (Bacillus strains) are acid-resistant and can be taken anytime.
Yes, temporary bloating, gas, or changes in bowel habits during the first 3-7 days is common and actually a positive sign. This 'die-off' reaction occurs as beneficial bacteria displace harmful organisms. If symptoms persist beyond 2 weeks, reduce the dose by half and gradually increase.
It depends on the strain. Most Lactobacillus and Bifidobacterium strains require refrigeration for viability. Spore-based probiotics (Bacillus) and Saccharomyces boulardii are shelf-stable. Check the label, if it says 'viable at time of manufacture' rather than 'at time of expiration,' refrigerate.
Yes, in fact, it's strongly recommended. Take the probiotic 2-3 hours apart from the antibiotic dose (so the antibiotic doesn't kill the probiotic). Saccharomyces boulardii is particularly resistant to antibiotics. Continue probiotics for at least 2-4 weeks after completing the antibiotic course.
For acute use (post-antibiotics, traveler's diarrhea), 4-8 weeks minimum. For chronic conditions (IBS, immune support), ongoing daily use is recommended. Probiotics don't permanently colonize, they exert benefits while you take them and for a limited time after stopping. Think of them as a daily maintenance supplement, not a one-time fix.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
