Vitamin D 5,000 i.u., 100 Tablets
Douglas Labs Vitamin D 5,000 IU delivers cholecalciferol (vitamin D3), the same form the body produces through sun exposure, in a clinically relevant dose.
May be a fit for
- Adults seeking to maintain vitamin D3 levels during low-sunlight months
- Individuals with limited outdoor exposure supporting healthy bone density
- Those following practitioner protocols requiring higher-dose vitamin D3 repletion
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Douglas Labs Vitamin D 5,000 IU delivers cholecalciferol (vitamin D3), the same form the body produces through sun exposure, in a clinically relevant dose. It supports calcium absorption, bone density maintenance, immune function, and mood regulation, particularly for adults with limited sun exposure, those in northern climates, or individuals with higher baseline needs.
Why It's Worth Considering: Douglas Labs is a practitioner-trusted manufacturer with rigorous quality standards; this 5,000 IU dose aligns with ranges commonly recommended by clinicians when addressing confirmed insufficiency under supervision.
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Douglas Labs · 100 TabletsMake it part of your routine.
As a dietary supplement, adults take 1 tablet daily with a meal or as directed by your health professional.
Important cautions & interactions
Product details
Supplement facts & complete label
Supplement Facts — Serving size: 1 tablet. Servings per container: 100. Vitamin D3 (as cholecalciferol): 125 mcg (5,000 IU), 625% Daily Value.
Other ingredients: microcrystalline cellulose, calcium carbonate, croscarmellose sodium, stearic acid, coating (hypromellose, glycerin), silica and vegetable stearate.
Label directions
As a dietary supplement, adults take 1 tablet daily with a meal or as directed by your health professional.
Label cautions
If you are pregnant or nursing, or if you are taking prescription medications, consult your health professional before using this supplement. People consuming more than 50 mcg (2,000 IU) per day should have their vitamin D blood levels monitored by a health professional. Keep out of the reach of children. Store in a cool, dry place. Use only if safety seal is intact.
Source: authorized supplier original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking to maintain vitamin D3 levels during low-sunlight months
- Individuals with limited outdoor exposure supporting healthy bone density
- Those following practitioner protocols requiring higher-dose vitamin D3 repletion
- Older adults supporting immune and musculoskeletal function with 5,000 IU D3
Considerations
- Hypercalcemia (elevated blood calcium)
- Sarcoidosis or other granulomatous diseases
- Severe kidney disease without medical supervision
- Taking thiazide diuretics (monitor calcium)
Compatibility & interactions
Works Well With
Take Separately From
No significant interactions identified. Always consult your healthcare provider.
What to expect over time
Serum Levels Rise
Measurable increase in 25(OH)D
Immune Support
Improved innate immune function
Mood & Energy
Reduced fatigue and improved mood
Optimal Range
Target 50-80 ng/mL achieved
Based on clinical studies on vitamin D3 supplementation. Response varies by baseline levels, body weight, and skin tone.
Compare the options
Compare Vitamin D Forms
D3 vs D2 vs D3+K2
| Feature | D3 (Cholecalciferol) | D2 (Ergocalciferol) | D3 + K2 Combo |
|---|---|---|---|
| Source | Animal (lanolin/lichen) | Plant/fungal | Animal + bacterial |
| Potency | 87% more effective at raising serum D | Baseline | Same as D3 + K2 synergy |
| Half-Life | ~2-3 weeks | ~2-3 days | ~2-3 weeks |
| Best For | General supplementation | Vegan-only option | Bone + cardiovascular health |
| Evidence | Strong (gold standard) | Moderate | Strong (synergistic) |
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Explore the source sentiment summary
Generally positive sentiment toward Vitamin D supplementation, though significant debate exists around optimal dosing versus official guidelines.
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A few useful answers.
Research & further reading
More category questions
How much vitamin D3 should I take daily?
Most functional medicine practitioners recommend 5,000 IU daily for adults with normal BMI, and up to 10,000 IU for those with obesity or severe deficiency. The Endocrine Society recommends maintaining serum 25(OH)D levels between 40-60 ng/mL. Test your levels every 3-6 months.
Is vitamin D3 better than D2?
Yes. D3 (cholecalciferol) is 87% more effective at raising and maintaining serum vitamin D levels compared to D2 (ergocalciferol). D3 also has a longer half-life. D2 is only preferred by strict vegans who cannot use lanolin-sourced D3 — lichen-based D3 is the vegan alternative.
Should I take vitamin D3 with vitamin K2?
Yes, especially at doses above 2,000 IU. Vitamin D3 increases calcium absorption from food. Without K2, that calcium can deposit in arteries instead of bones. K2 (MK-7 form) activates osteocalcin (puts calcium in bones) and matrix GLA protein (keeps calcium out of arteries).
Can I take too much vitamin D?
Toxicity is rare below 10,000 IU/day in healthy adults but possible with chronic high-dose use without monitoring. Symptoms of excess include hypercalcemia (nausea, kidney stones, confusion). Always pair high-dose D3 with K2 and test 25(OH)D levels every 3-6 months.
When is the best time to take vitamin D3?
Take with your largest meal containing fat — D3 is fat-soluble and absorption increases 30-50% when taken with dietary fat. Morning or afternoon is preferred over evening, as some studies suggest late-night D3 may interfere with melatonin production.
How long does it take for vitamin D levels to increase?
Serum 25(OH)D typically rises within 1-2 weeks of supplementation. Reaching optimal range (50-80 ng/mL) takes 2-3 months at 5,000 IU/day from a deficient baseline. Higher loading doses (10,000 IU for 8 weeks then maintenance) can accelerate this.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.