Probiotic Pearls, 90 Capsules
Probiotic Pearls by Integrative Therapeutics delivers live probiotic cultures in a small, easy-to-swallow softgel using a patented True Delivery technology, a triple-layer encapsulation designed to protect bacteria from stomach acid and support their arrival in the intestinal tract.
May be a fit for
- Adults seeking daily probiotic support in a convenient pearl form
- Individuals maintaining digestive comfort with Lactobacillus and Bifidobacterium strains
- Practitioners protocols requiring shelf-stable probiotic delivery for sensitive patients
Save together with Wellness Circles
Invite friends or family to a Wellness Circle. Your group can unlock savings together. See current tiers and terms before joining.
Explore Wellness CirclesA closer look.
Probiotic Pearls by Integrative Therapeutics delivers live probiotic cultures in a small, easy-to-swallow softgel using a patented True Delivery technology, a triple-layer encapsulation designed to protect bacteria from stomach acid and support their arrival in the intestinal tract. Formulated for adults seeking convenient, daily digestive and immune support.
Why It's Worth Considering: The pearl-format encapsulation eliminates the need for refrigeration while helping maintain organism viability through the digestive environment, a practical advantage over many standard capsule-based probiotics.
Integrative Therapeutics · 90 CapsulesMake it part of your routine.
Adults swallow 1 capsule daily with water or another beverage, or as recommended by a healthcare professional. May be taken with or without food. Do not chew or crush.
Important cautions & interactions
Product details
Supplement facts & complete label
Supplement Facts — Serving size: 1 capsule. Servings per container: 90.
Proprietary probiotic blend providing 1 billion CFU — Bifidobacterium longum BB536 and HOWARU® Lactobacillus acidophilus NCFM®: 11 mg.
Other ingredients: palm oil, fish gelatin, glycerin, sunflower lecithin, pectin.
Label directions
Adults swallow 1 capsule daily with water or another beverage, or as recommended by a healthcare professional. May be taken with or without food. Do not chew or crush.
Label cautions
If pregnant, nursing, or taking medications, consult a healthcare professional before use. Keep out of reach of children. Do not use if the tamper-evident foil or plastic is punctured. Store at room temperature; avoid excessive heat and direct sunlight.
Source: Integrative Therapeutics manufacturer product page · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking daily probiotic support in a convenient pearl form
- Individuals maintaining digestive comfort with Lactobacillus and Bifidobacterium strains
- Practitioners protocols requiring shelf-stable probiotic delivery for sensitive patients
- Those supporting gut microbiome balance without refrigeration requirements
Considerations
- Severely immunocompromised (consult physician)
- Active pancreatitis
- Central venous catheters (risk of translocation)
- SIBO (some probiotics may worsen — consult practitioner)
Compatibility & interactions
Works Well With
Take Separately From
No significant interactions identified. Always consult your healthcare provider.
What to expect over time
Colonization Begins
Beneficial bacteria begin establishing colonies
GI Improvement
Reduced bloating, improved regularity
Immune Modulation
Enhanced immune markers, fewer infections
Microbiome Shift
Sustained diversity improvement
Based on clinical probiotic research. Initial die-off symptoms (temporary bloating) may occur in the first week.
Compare the options
Compare Probiotic Types
Which strain type is right for you?
| Feature | Multi-Strain (this) | Spore-Based | Saccharomyces | Single-Strain |
|---|---|---|---|---|
| Survivability | Moderate (refrigerate) | Excellent (shelf-stable) | Excellent (yeast-based) | Moderate |
| Best For | General gut health | Antibiotic recovery | Diarrhea, C. diff | Targeted conditions |
| CFU Range | 10-100 billion | 2-5 billion (potent) | 5-10 billion | 1-50 billion |
| Research | Extensive | Growing | Strong (S. boulardii) | Strain-specific |
Explore complementary products
Metabolic Maintenance - BioMaintenance™ Prebiotic + Fiber, 378 gPrebiotics are food for probiotics. Taking them together (synbiotic approach) increases colonization success by 3-5x.$55.99
Thorne - Advanced Digestive Enzymes (formerly Bio-Gest), 180 CapsulesEnzymes break down food while probiotics optimize the microbiome. Together they address both mechanical and microbial digestion.$56.99
Thorne - L-Glutamine Powder, 513 gGlutamine repairs intestinal permeability (leaky gut) while probiotics restore microbial balance — the two pillars of gut healing.$67.99
Metagenics - Zinc Carnosine Complex, 60 TabletsZinc carnosine protects and heals the stomach and intestinal lining, creating a healthier environment for probiotic colonization.$65.99Real reviews. A wider perspective.
Customer reviews, social conversations and expert insights, with every source in view.
- Marketplaces & brand websites
- Amazon, iHerb and direct brand reviews
- Social & community
- Reddit, X, Instagram and TikTok
- Video & creators
- YouTube and creator perspectives
Coverage varies by product and brand.
These are broader practitioner and research perspectives. They may discuss the brand or other products, rather than this exact formula.
A few useful answers.
Research & further reading
More category questions
How many CFU do I need in a probiotic?
For general health maintenance, 10-20 billion CFU is sufficient. For therapeutic use (post-antibiotics, IBS, immune support), 50-100 billion CFU is recommended. More important than CFU count is strain diversity and survivability — a 5 billion spore-based probiotic may be more effective than a 100 billion conventional strain that doesn't survive stomach acid.
Should I take probiotics with food or on an empty stomach?
Take with food or within 30 minutes of eating. Food buffers stomach acid and increases probiotic survival by up to 100x. A small amount of fat in the meal further improves survival. Exception: spore-based probiotics (Bacillus strains) are acid-resistant and can be taken anytime.
Can probiotics cause bloating at first?
Yes — temporary bloating, gas, or changes in bowel habits during the first 3-7 days is common and actually a positive sign. This 'die-off' reaction occurs as beneficial bacteria displace harmful organisms. If symptoms persist beyond 2 weeks, reduce the dose by half and gradually increase.
Do I need to refrigerate probiotics?
It depends on the strain. Most Lactobacillus and Bifidobacterium strains require refrigeration for viability. Spore-based probiotics (Bacillus) and Saccharomyces boulardii are shelf-stable. Check the label — if it says 'viable at time of manufacture' rather than 'at time of expiration,' refrigerate.
Can I take probiotics with antibiotics?
Yes — in fact, it's strongly recommended. Take the probiotic 2-3 hours apart from the antibiotic dose (so the antibiotic doesn't kill the probiotic). Saccharomyces boulardii is particularly resistant to antibiotics. Continue probiotics for at least 2-4 weeks after completing the antibiotic course.
How long should I take probiotics?
For acute use (post-antibiotics, traveler's diarrhea), 4-8 weeks minimum. For chronic conditions (IBS, immune support), ongoing daily use is recommended. Probiotics don't permanently colonize — they exert benefits while you take them and for a limited time after stopping. Think of them as a daily maintenance supplement, not a one-time fix.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.