Practitioner-grade vitamin d3 with k2 by Ortho Molecular Products
Serving Size:
1 Drop (0.025 mL)
Amount Per Serving:
Vitamin D (D3 as Cholecalciferol) ... 25 mcg (1,000 IU)
Vitamin K2 (as Menaquinone-7 (MK-7)) (MenaQ7®PRO) ... 10 mcg
Other Ingredients:
Medium Chain Triglycerides.
Does Not Contain: Gluten, corn, yeast, artificial colors or flavors
DO NOT ACCEPT IF LABEL SHOWS SIGNS OF TAMPERING
WARNING: all forms of Vitamin K may interact with blood thinning medications. If you are taking such medications, please consult your physician before taking this product.
As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.
KEEP CONTAINER TIGHTLY CLOSED. STORE AT ROOM TEMPERATURE. KEEP OUT OF REACH OF CHILDREN.
This product was sealed for your protection. Do not use if outer logoed neck seal is missing or damaged.
1 drop (0.025 mL) per day or as recommended by your health care professional. Can be taken directly on the tongue and swallowed or mixed with the beverage of your choice.
Ingredient information is provided above. A clear label image is not available yet.
View original supplier image (quality may be limited)Source: Fullscript supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Ortho Molecular Products' Vitamin D3 with K2 pairs cholecalciferol (D3) with menaquinone-7 (MK-7), the long-acting form of vitamin K2, to support calcium metabolism, bone density, and cardiovascular health. This combination is formulated for individuals seeking synergistic support for skeletal integrity and soft-tissue calcium distribution.
Why It's Worth Considering: Ortho Molecular is a practitioner-trusted brand known for tightly controlled manufacturing standards; pairing D3 with MK-7 specifically addresses the concern that high-dose D3 supplementation should be balanced with K2 to support proper calcium utilization.
1 drop (0.025 mL) per day or as recommended by your health care professional. Can be taken directly on the tongue and swallowed or mixed with the beverage of your choice.
| Feature | D3 (Cholecalciferol) | D2 (Ergocalciferol) | D3 + K2 Combo |
|---|---|---|---|
| Source | Animal (lanolin/lichen) | Plant/fungal | Animal + bacterial |
| Potency | 87% more effective at raising serum D | Baseline | Same as D3 + K2 synergy |
| Half-Life | ~2-3 weeks | ~2-3 days | ~2-3 weeks |
| Best For | General supplementation | Vegan-only option | Bone + cardiovascular health |
| Evidence | Strong (gold standard) | Moderate | Strong (synergistic) |
Most functional medicine practitioners recommend 5,000 IU daily for adults with normal BMI, and up to 10,000 IU for those with obesity or severe deficiency. The Endocrine Society recommends maintaining serum 25(OH)D levels between 40-60 ng/mL. Test your levels every 3-6 months.
Yes. D3 (cholecalciferol) is 87% more effective at raising and maintaining serum vitamin D levels compared to D2 (ergocalciferol). D3 also has a longer half-life. D2 is only preferred by strict vegans who cannot use lanolin-sourced D3, lichen-based D3 is the vegan alternative.
Yes, especially at doses above 2,000 IU. Vitamin D3 increases calcium absorption from food. Without K2, that calcium can deposit in arteries instead of bones. K2 (MK-7 form) activates osteocalcin (puts calcium in bones) and matrix GLA protein (keeps calcium out of arteries).
Toxicity is rare below 10,000 IU/day in healthy adults but possible with chronic high-dose use without monitoring. Symptoms of excess include hypercalcemia (nausea, kidney stones, confusion). Always pair high-dose D3 with K2 and test 25(OH)D levels every 3-6 months.
Take with your largest meal containing fat, D3 is fat-soluble and absorption increases 30-50% when taken with dietary fat. Morning or afternoon is preferred over evening, as some studies suggest late-night D3 may interfere with melatonin production.
Serum 25(OH)D typically rises within 1-2 weeks of supplementation. Reaching optimal range (50-80 ng/mL) takes 2-3 months at 5,000 IU/day from a deficient baseline. Higher loading doses (10,000 IU for 8 weeks then maintenance) can accelerate this.
This product is in the Apotheca marketplace and has been assigned a Quality & Trust Score of 80 based on brand quality signals and category baseline. Detailed reviews from Amazon, iHerb, Reddit, practitioner citations, and clinical research will appear here as they're aggregated.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
