Capsules · 60 capsules · 60 servings · $2.31/serving
Serving Size:
1 capsule
Amount Per Serving:
Coenzyme Q10 ... 250 mg
Other Ingredients:
vegetarian capsule (cellulose, water)
If pregnant or lactating, consult your physician before taking this product.
CoQ10 may react with blood thinning medications. Consult your physician for more information.
*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Take 1–2 capsules per day, in divided doses, with meals.
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Source: Fullscript supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Pure Encapsulations CoQ10 250mg delivers coenzyme Q10 in a clinically relevant dose to support cellular energy production and cardiovascular health. CoQ10 is a fat-soluble compound central to mitochondrial ATP synthesis, making it relevant for adults with higher energy demands, those on statin therapy, or anyone seeking to maintain antioxidant defenses as levels naturally decline with age.
Why It's Worth Considering: Pure Encapsulations is a practitioner-trusted brand formulated without common excipients, fillers, or artificial additives, and the 250mg dose provides meaningful potency in a single capsule.
Take 1–2 capsules per day, in divided doses, with meals.
| Feature | Ubiquinol (reduced) | Ubiquinone (oxidized) | With PQQ |
|---|---|---|---|
| Bioavailability | 3-8x higher absorption | Standard (baseline) | Ubiquinol + PQQ synergy |
| Best For | Over 40, statin users | Budget, under 40 | Mitochondrial biogenesis |
| Form | Active (ready to use) | Must be converted by body | Dual mechanism |
| Evidence | Strong (preferred) | Strong (well-studied) | Emerging (promising) |
Ubiquinol is the reduced (active) form of CoQ10, your body can use it directly. Ubiquinone is the oxidized form that must be converted to ubiquinol before use. After age 40, this conversion becomes less efficient, making ubiquinol the preferred form. Ubiquinol has 3-8x higher bioavailability than ubiquinone.
Yes, strongly recommended. Statins block the mevalonate pathway which produces both cholesterol AND CoQ10. Statin use can reduce CoQ10 levels by 40%, contributing to muscle pain, fatigue, and weakness. Most cardiologists now recommend CoQ10 supplementation alongside statin therapy. 100-200mg ubiquinol daily is standard.
For general health: 100mg ubiquinol daily. For statin users: 100-200mg. For heart failure or cardiovascular support: 200-300mg. For migraines: 300-400mg. Always take with a fat-containing meal for best absorption, CoQ10 is fat-soluble.
Meta-analyses show CoQ10 can reduce systolic blood pressure by 3-5 mmHg and diastolic by 1-3 mmHg over 4-12 weeks at doses of 100-300mg/day. It's not a replacement for blood pressure medication but a useful adjunct. If you're on BP meds, monitor for additive hypotensive effects.
Take with your largest meal containing fat, CoQ10 is fat-soluble and absorption improves dramatically with dietary fat. Morning or afternoon is preferred, as CoQ10 supports energy production and may cause mild alertness. Avoid taking late at night.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
