Pancreatic Enzymes (formerly Dipan-9), 180 Capsules
Size: 180 capsules
May be a fit for
- Adults seeking pancreatic enzyme support for comfortable fat digestion
- Individuals who experience bloating or heaviness after high-fat meals
- Practitioner protocols requiring full-spectrum lipase, amylase, and protease support
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Thorne Pancreatic Enzymes (formerly Dipan-9) is a concentrated pancreatin supplement providing protease, lipase, and amylase to support the digestion of proteins, fats, and carbohydrates. Formulated for individuals with digestive insufficiency concerns, it delivers broad-spectrum enzymatic activity in a convenient capsule form.
Why It's Worth Considering: Thorne's practitioner-grade manufacturing standards and the high-potency pancreatin concentrate make this a reliable option for clinicians and health-conscious individuals seeking meaningful enzymatic support rather than a low-dose formula.
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Our curation and trust scoring bring together manufacturing, testing, research, practitioner insight and reviews from across the web.
Our score is an editorial assessment, not a product certification or a guarantee of results.
Thorne · 180 CapsulesMake it part of your routine.
Take 1-2 capsules with each meal or as recommended by your health-care practitioner.
Important cautions & interactions
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health-care practitioner before using this product.
ADDITIONAL WARNINGS
It is not recommended to remove the Pancreatic Enzymes powder from the capsule to take orally, as it can be irritating to the oral mucosa.
Product details
Supplement facts & complete label
Supplement Facts
Serving size: 2 capsules. Servings per container: 90.
Pancreatin (porcine) 1 g. Daily value not established.
Other ingredients: Hypromellose capsule.
Label directions
Take 1-2 capsules with each meal or as recommended by your health-care practitioner.
Label cautions
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health-care practitioner before using this product.
ADDITIONAL WARNINGS
It is not recommended to remove the Pancreatic Enzymes powder from the capsule to take orally, as it can be irritating to the oral mucosa.
Source: Thorne manufacturer product label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Who it may suit
May be a fit for
- Adults seeking pancreatic enzyme support for comfortable fat digestion
- Individuals who experience bloating or heaviness after high-fat meals
- Practitioner protocols requiring full-spectrum lipase, amylase, and protease support
- Those with lower endogenous pancreatic output seeking digestive enzyme replenishment
Considerations
- Active stomach or duodenal ulcers (especially betaine HCl)
- Taking blood thinners (some enzymes have mild anti-platelet activity)
- Active pancreatitis
Explore complementary products
NOW Foods - Aloe 10,000 & Probiotics, 60 CapsulesEnzymes break down food mechanically while probiotics optimize the microbiome. Together they address both aspects of digestion.$19.99
Thorne - L-Glutamine Powder, 513 gEnzymes improve digestion while glutamine repairs the intestinal lining. The two-pronged approach to gut healing.$67.99
Thorne - Betaine HCL & Pepsin, 225 CapsulesMany people have LOW stomach acid (not high). Betaine HCl restores acid while enzymes handle the downstream breakdown.$47.99Real reviews. A wider perspective.
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Coverage varies by product and brand.
243 product and brand ratings and mentions across 6 sources.
These are broader practitioner and research perspectives. They may discuss the brand or other products, rather than this exact formula.
Explore the source sentiment summary
Predominantly negative sentiment driven by PE acquisition fears, COA transparency issues, and Amazon counterfeits; few organic positive voices.
This summary includes broader brand discussion. Individual experiences are not evidence of product effectiveness.
A few useful answers.
Research & further reading
More category questions
When should I take digestive enzymes?
Take immediately before or with the first bites of your meal. Enzymes need to be in the stomach when food arrives. Taking them after eating is less effective. For best results, take with every substantial meal — especially meals high in fat, protein, or hard-to-digest foods.
Do I need enzymes if I take probiotics?
They serve different functions. Enzymes physically break down food into absorbable nutrients. Probiotics are living bacteria that optimize the gut microbiome, produce vitamins, and support immune function. Many gut issues benefit from both — especially after age 40 when natural enzyme production declines.
Can I become dependent on digestive enzymes?
No. Digestive enzymes do not cause your body to produce fewer of its own enzymes. They supplement what your body is already making (or under-making). You can stop taking them anytime without withdrawal or rebound. If your symptoms return after stopping, it means you still need the support — not that you've become dependent.
Supplement information is provided for education and is not a substitute for personalized medical advice. Supplements are not intended to diagnose, treat, cure or prevent disease. Read the current product label before use.