Capsules · 60 capsules · 60 servings · $0.46/serving
Serving Size:
1 capsule
Amount Per Serving:
Vitamin D3 … 250mcg (10000IU)
(as cholecalciferol)
Other Ingredients:
Hypromellose, Rice Powder, Ascorbyl Palmitate.
Free from casein, corn, crustacean, dairy/milk, egg, fish, artificial colors/flavors, gluten, lactose, peanut, sesame, shellfish, soy, soy protein, sugar, sweeteners, tree nut, wheat, and unnecessary excipients. Vegetarian and non-GMO.
Store sealed in a cool dry place. Keep out of reach of children. Use only if safety seal is intact.
Warning: If you are pregnant or lactating, taking medication or have a medical condition, consult your healthcare practitioner before use.
Take 1 vegetarian capsule daily or as directed by your healthcare professional.
Ingredient information is provided above. A clear label image is not available yet.
View original supplier image (quality may be limited)Source: Fullscript supplier catalog · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Vital Nutrients Vitamin D3 10,000 IU delivers cholecalciferol, the same form the body synthesizes from sunlight, in a high-potency softgel designed for adults working with a practitioner to address significant vitamin D insufficiency. As a practitioner-grade brand, Vital Nutrients formulates to pharmaceutical-grade standards with rigorous third-party testing. This product supports calcium absorption, bone density maintenance, and healthy immune function.
Why It's Worth Considering: The cholecalciferol form is well-recognized for superior bioavailability compared to D2, and the 10,000 IU dose is formulated for supervised, therapeutic-range repletion rather than everyday maintenance.
Take 1 vegetarian capsule daily or as directed by your healthcare professional.
| Feature | D3 (Cholecalciferol) | D2 (Ergocalciferol) | D3 + K2 Combo |
|---|---|---|---|
| Source | Animal (lanolin/lichen) | Plant/fungal | Animal + bacterial |
| Potency | 87% more effective at raising serum D | Baseline | Same as D3 + K2 synergy |
| Half-Life | ~2-3 weeks | ~2-3 days | ~2-3 weeks |
| Best For | General supplementation | Vegan-only option | Bone + cardiovascular health |
| Evidence | Strong (gold standard) | Moderate | Strong (synergistic) |
Most functional medicine practitioners recommend 5,000 IU daily for adults with normal BMI, and up to 10,000 IU for those with obesity or severe deficiency. The Endocrine Society recommends maintaining serum 25(OH)D levels between 40-60 ng/mL. Test your levels every 3-6 months.
Yes. D3 (cholecalciferol) is 87% more effective at raising and maintaining serum vitamin D levels compared to D2 (ergocalciferol). D3 also has a longer half-life. D2 is only preferred by strict vegans who cannot use lanolin-sourced D3, lichen-based D3 is the vegan alternative.
Yes, especially at doses above 2,000 IU. Vitamin D3 increases calcium absorption from food. Without K2, that calcium can deposit in arteries instead of bones. K2 (MK-7 form) activates osteocalcin (puts calcium in bones) and matrix GLA protein (keeps calcium out of arteries).
Toxicity is rare below 10,000 IU/day in healthy adults but possible with chronic high-dose use without monitoring. Symptoms of excess include hypercalcemia (nausea, kidney stones, confusion). Always pair high-dose D3 with K2 and test 25(OH)D levels every 3-6 months.
Take with your largest meal containing fat, D3 is fat-soluble and absorption increases 30-50% when taken with dietary fat. Morning or afternoon is preferred over evening, as some studies suggest late-night D3 may interfere with melatonin production.
Serum 25(OH)D typically rises within 1-2 weeks of supplementation. Reaching optimal range (50-80 ng/mL) takes 2-3 months at 5,000 IU/day from a deficient baseline. Higher loading doses (10,000 IU for 8 weeks then maintenance) can accelerate this.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
