Capsules · 60 capsules
Supplement Facts — Serving size: 2 capsules. Thiamin: 5.2 mg. Riboflavin (as riboflavin-5-phosphate): 13.1 mg. Niacin (as niacinamide): 12 mg. Vitamin B6 (as pyridoxal-5-phosphate): 63 mg. Folate (as [6S]-5-methyltetrahydrofolate glucosamine salt): 900 mcg DFE. Vitamin B12 (as methylcobalamin): 20 mcg. Biotin: 300 mcg. Pantothenic acid: 15 mg. Ancient Nutrients TCM blend: 973 mg — bovine liver, beef bone broth, chicken bone broth, organic astragalus root extract, organic fo-ti root extract, organic green tea leaf extract, organic schisandra berry extract, organic reishi mushroom extract, wild hake roe. Other ingredients: Saccharomyces cerevisiae, gelatin. Contains hake.
Adults take 2 capsules daily with 8 ounces of water or another beverage, with or without food.
Contains hake. Consult your healthcare practitioner before use, especially if pregnant, nursing, or under medical supervision. Do not use if opened or tampered with. Keep out of reach of children. Store in a cool, dry place.
Source: Fullscript exact-SKU catalog label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Ancient Nutrition's B Complex delivers a full-spectrum blend of B vitamins in a whole-food fermented form, designed to support energy metabolism, nervous system function, and cognitive performance. The fermentation process is central to this brand's approach, aimed at enhancing nutrient bioavailability in a way that mimics food-based B vitamin sources. It's a natural fit for those who prefer whole-food-style supplementation over isolated synthetic forms.
Why It's Worth Considering: Ancient Nutrition uses a proprietary fermentation and organic whole-food blend, which may improve tolerability and absorption compared to conventional B complex formulas.
Adults take 2 capsules daily with 8 ounces of water or another beverage, with or without food.
| Feature | Methylated (active) | Standard | Synthetic (cheap) |
|---|---|---|---|
| B12 Form | Methylcobalamin | Hydroxocobalamin | Cyanocobalamin |
| Folate Form | 5-MTHF (methylfolate) | Folinic acid | Folic acid (synthetic) |
| B6 Form | P-5-P (pyridoxal-5-phosphate) | Pyridoxal | Pyridoxine HCl |
| Best For | MTHFR variants, optimal absorption | General use | Budget (requires conversion) |
| MTHFR Safe | Yes — bypasses mutation | Mostly yes | No — cannot be converted by 40% of population |
Methylated B vitamins are in their active, bioavailable form, your body can use them immediately without conversion. About 40% of the population has MTHFR gene variants that impair conversion of synthetic folic acid to active folate. Methylated forms (methylcobalamin, methylfolate, P-5-P) bypass this issue entirely.
This is completely normal and harmless. Riboflavin (B2) is a bright yellow fluorescent compound. When you take more than your body needs, the excess is excreted in urine, causing the distinctive color. It's actually a sign your body absorbed the B vitamins and is eliminating what it doesn't need.
B vitamins support energy production, so morning dosing is generally recommended. Some people find evening B-complex disrupts sleep due to increased energy. However, B6 and B12 are involved in melatonin production, so individual responses vary. If evening dosing doesn't affect your sleep, it's fine.
Signs of B12 deficiency: fatigue, brain fog, tingling/numbness in extremities, balance issues, mood changes, and pale skin. At-risk groups: vegetarians/vegans (B12 is only in animal foods), adults over 50 (reduced absorption), and those taking metformin or PPIs (which deplete B12). A serum B12 test plus methylmalonic acid (more sensitive) can confirm.
Yes, B vitamins are water-soluble, meaning excess is excreted daily. No accumulation risk at standard supplement doses. The exception is B6 (pyridoxine): chronic doses above 100mg/day can cause peripheral neuropathy (nerve damage). The P-5-P form is safer at higher doses than pyridoxine HCl.
Ask Gabriel for personalized stacking recommendations.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
