Capsules · 90 capsules
Serving Size:
3 Capsules
Amount Per Serving:
Thiamine (B1 as Benfotiamine) ... 100 mg
Riboflavin (B2 as Riboflavin-5-phosphate sodium) ... 7.5 mg
Niacin (B3 from 129 mg inositol hexanicotinate per capsule) ... 353 mg
B6 (as Pyridoxal-5'-phosphate) ... 100 mg
Folic acid (as calcium L-5-MTHF) ... 1000 mcg
B12 (as Methylcobalamin) ... 1000 mcg
Biotin ... 500 mcg
Pantothenic acid (B5 as calcium D-pantothenate, Pantethine) ... 300 mg
Choline bitartrate ... 600 mg
Inositol (as inositol, inositol hexanicotinate) ... 393 mg
Amino Acid Profile
Inositol hexanicotinate ... 28 mg
Inositol ... 103 mg
Other Ingredients:
microcrystalline cellulose, dicalcium phosphate, silicon dioxide, hydroxypropyl cellulose and sodium stearyl fumarate.
Take one capsule one to three times daily with food, or as directed by a qualified health care practitioner.
Consult a health care practitioner before use if you are pregnant, lactating, have a medical condition, or if you’re taking any medication. Keep out of reach of children.
Source: Fullscript original manufacturer label · September 06, 2026. Formulas and labels can change. Check the packaging you receive.
Advanced B Complex™ from AOR US delivers a full-spectrum B vitamin formula featuring active, coenzymated forms, including methylfolate, methylcobalamin, pyridoxal-5-phosphate, and riboflavin-5-phosphate, designed to support energy metabolism, nervous system function, and homocysteine balance. It's formulated for individuals who may have difficulty converting standard B vitamins into their biologically active forms.
Why It's Worth Considering: The use of coenzymated B vitamins bypasses the conversion steps required by synthetic precursors, making them more readily utilizable, a meaningful distinction for those with MTHFR variants or compromised methylation capacity.
Take one capsule one to three times daily with food, or as directed by a qualified health care practitioner.
| Feature | Methylated (active) | Standard | Synthetic (cheap) |
|---|---|---|---|
| B12 Form | Methylcobalamin | Hydroxocobalamin | Cyanocobalamin |
| Folate Form | 5-MTHF (methylfolate) | Folinic acid | Folic acid (synthetic) |
| B6 Form | P-5-P (pyridoxal-5-phosphate) | Pyridoxal | Pyridoxine HCl |
| Best For | MTHFR variants, optimal absorption | General use | Budget (requires conversion) |
| MTHFR Safe | Yes — bypasses mutation | Mostly yes | No — cannot be converted by 40% of population |
Methylated B vitamins are in their active, bioavailable form, your body can use them immediately without conversion. About 40% of the population has MTHFR gene variants that impair conversion of synthetic folic acid to active folate. Methylated forms (methylcobalamin, methylfolate, P-5-P) bypass this issue entirely.
This is completely normal and harmless. Riboflavin (B2) is a bright yellow fluorescent compound. When you take more than your body needs, the excess is excreted in urine, causing the distinctive color. It's actually a sign your body absorbed the B vitamins and is eliminating what it doesn't need.
B vitamins support energy production, so morning dosing is generally recommended. Some people find evening B-complex disrupts sleep due to increased energy. However, B6 and B12 are involved in melatonin production, so individual responses vary. If evening dosing doesn't affect your sleep, it's fine.
Signs of B12 deficiency: fatigue, brain fog, tingling/numbness in extremities, balance issues, mood changes, and pale skin. At-risk groups: vegetarians/vegans (B12 is only in animal foods), adults over 50 (reduced absorption), and those taking metformin or PPIs (which deplete B12). A serum B12 test plus methylmalonic acid (more sensitive) can confirm.
Yes, B vitamins are water-soluble, meaning excess is excreted daily. No accumulation risk at standard supplement doses. The exception is B6 (pyridoxine): chronic doses above 100mg/day can cause peripheral neuropathy (nerve damage). The P-5-P form is safer at higher doses than pyridoxine HCl.
Ask Gabriel for personalized stacking recommendations.
No significant interactions identified. Always consult your healthcare provider.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
